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|Antigen||Interleukin 2 Receptor, beta (IL2RB) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL2 Receptor beta antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-IL2 Receptor beta AntibodyTarget Details IL2 Receptor beta Application Details Handling Images
|Specificity||This antibody detects endogenous levels of IL-2Rβ protein.|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purification||Affinity chromatography using epitope-specific immunogen|
|Purity||> 95 % (by SDS-PAGE)|
Target Details IL2 Receptor betaProduct Details anti-IL2 Receptor beta Antibody Application Details Handling Images back to top
|Alternative Name||CD122 / IL2RB (IL2RB Antibody Abstract)|
|Background||The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75|
|Molecular Weight||approx. 60 kDa|
|Pathways||JAK-STAT Signaling, Growth Factor Binding|
Application DetailsProduct Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling Images back to top
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling back to top