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|Antigen||Interleukin 21 (IL21) Antibodies|
|Epitope||Intermediate Domain Alternatives|
|Conjugate||This IL21 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
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Product Details anti-IL21 AntibodyTarget Details IL21 Application Details Handling Images
|Specificity||IL-21 antibody was raised against a synthetic peptide corresponding to 15 amino acids near the center of human IL-21 precursor.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||Human IL-21 (Intermediate Domain) Peptide|
Target Details IL21Product Details anti-IL21 Antibody Application Details Handling Images back to top
|Alternative Name||Interleukin-21 / IL21 (IL21 Antibody Abstract)|
|Background||A novel cytokine was recently identified in human and mouse and designated IL-21 , which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21, Za11|
|Pathways||JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response|
Application DetailsProduct Details anti-IL21 Antibody Target Details IL21 Handling Images back to top
ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 18 kDa band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL21 Antibody Target Details IL21 Application Details Images back to top
|Buffer||PBS containing 0.02 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|