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Mouse (Murine) IL5 Protein expressed in Escherichia coli (E. coli) - ABIN1305123
Kinashi, Harada, Severinson, Tanabe, Sideras, Konishi, Azuma, Tominaga, Bergstedt-Lindqvist, Takahashi: Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. in Nature 1986
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Human IL5 Protein expressed in Escherichia coli (E. coli) - ABIN1305122
Kitamura, Takaku, Miyajima: IL-1 up-regulates the expression of cytokine receptors on a factor-dependent human hemopoietic cell line, TF-1. in International immunology 1991
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Human IL5 Protein expressed in Escherichia coli (E. coli) - ABIN1112346
Xin, Mizukami, Urabe, Toda, Shinoda, Yoshida, Oomura, Kojima, Ichino, Klinman, Ozawa, Okuda: Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells. in Journal of virology 2006
Serum IL-5 and IL-13 (show IL13 Proteins) are reliable biomarkers for the blood eosinophilia asthma phenotype.
Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 and GM-CSF (show CSF2 Proteins).
simvastatin was demonstrated to inhibit IL-5-induced CCR3 (show CCR3 Proteins) expression and chemotaxis of eosinophils mediated via the mevalonate pathway.
Interleukin-5/-targeted treatments offer promises to patients with eosinophilic respiratory disorders; review
Data indicate that interleukin 5 (IL-5)-associated single nucleotide polymorphisms (SNPs) were not associated with carotid intima-media thickness.
Post-liver transplant patients with food allergy showed a unique cytokine profile in response to various stimuli, with extremely elevated IL-5, low IL-10 (show IL10 Proteins) secretion.
high levels of IL-33 (show IL33 Proteins) and a high IL-33 (show IL33 Proteins)/soluble ST2 (show SULT2A1 Proteins) ratio correlates with elevated levels of IFN-gamma (show IFNG Proteins), TNF-alpha (show TNF Proteins) and IL-17alpha as well as IL-5, demonstrating that IL-33 (show IL33 Proteins) has pleiotropic effects.
Production of IL-5 in response to both extract and the Bet v1-derived peptide mix strongly suggested that T cells were a major source of IL-5.
TRPV1 (show TRPV1 Proteins) expression level, IL-4 (show IL4 Proteins) level, and rs4790522 site mutation are the main risk factors inducing bronchial asthma in children
It has been shown in this study that the level of IL-5, one of the markers of eosinophilic inflammation, is higher in EBC of children with atopic asthma than in those with nonatopic asthma.
these studies establish a basal defect in eosinophilopoiesis in IL-33 (show IL33 Proteins)- and ST2 (show SULT2A1 Proteins)-deficient mice and a mechanism whereby IL-33 (show IL33 Proteins) supports eosinophils by driving both systemic IL-5 production and the expansion of IL-5Ralpha-expressing precursor cells
Increased production of IL-5 from Peyer's patch cells and the restored Th1-type immune response might cause the production of abnormal IgA and might induce the glomerular deposition of IgA in IGA nephropathy.
E. granulosus infection remarkably reduces the severity of OVA-induced airway inflammation likely through enhancing IL-10 (show IL10 Proteins) and down-regulation of IL-5 and IL-17A (show IL17A Proteins).
selective proliferation of IgM (show CD40LG Proteins) rheumatoid factor-secreting B-1a cells is induced by co-stimulation by the specific pathogen antigen and IL-5 in the development of MC in Capillaria hepatica-infected mice
IL5, a cytokine involved in allergic and infectious diseases, facilitates metastatic colonization through recruitment of sentinel eosinophils and regulation of other inflammatory/immune cells in the microenvironment of the distal lung.
In mice, low-dose IL-2 (show IL2 Proteins)-anti-IL-2 (show IL2 Proteins) antibody complexes drove group 2 innate lymphoid cells (ILC2) to produce IL-5 and proliferate.
Data (including data from knockout mice) suggest that up-regulation of IL5 production in lungs during influenza virus infection is due to infiltration of natural killer cells and alveolar macrophages into infected lung tissue.
A decrease in the levels of IL-5, IL-9 (show IL9 Proteins), and IL-6R in the BALF.
eosinophils express CAR4 (show CA4 Proteins) following IL-5 or allergen exposure, and that CAR4 (show CA4 Proteins) is involved in regulating the lung transcriptome associated with allergic airway inflammation
This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 (show IL4 Proteins) or IL-5.
The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
B-cell differentiation factor I
, T-cell replacing factor
, eosinophil differentiation factor
, B-cell growth factor II
, cytotoxic T-lymphocyte inducer
, Interleukin 5 (colony-stimulating factor eosinophil)
, Interleukin 5 (colony-stimulating factor, eosinophil)
, colony-stimulating factor, eosinophil
, interleukin 5
, interleukin 5 (colony-stimulating factor, eosinophil)