anti-Mouse (Murine) IL7R antibody for ELISA (Detection)

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • IL7R
  • CD127
  • IL-7Ralpha
  • CDW127
  • IL-7R-alpha
  • IL7RA
  • ILRA
  • IL-7RA
  • interleukin 7 receptor
  • IL7R
  • Il7r
Reactivity
Mouse (Murine)
236
220
46
3
2
1
1
Host
Rat
141
127
119
18
7
4
Clonality
Monoclonal
Conjugate
This IL7R antibody is conjugated to PE
29
25
24
23
19
17
11
10
9
9
8
7
6
6
6
6
5
5
5
5
5
5
5
4
2
2
2
2
2
2
2
2
1
1
1
1
Application
ELISA (Detection)
203
186
74
67
49
26
14
12
12
11
7
5
4
3
3
3
2
2
2
1
1
1
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Catalog No. ABIN2662997
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2662995 ELISA (Detection) WB PE Rat IgG2a kappa Log in to see A7R34 6
1 ABIN2662998 ELISA (Detection) PE Rat IgG2b kappa Log in to see SB-199 9
1 ABIN2662996 ELISA (Detection) WB PE Rat IgG2a kappa Log in to see A7R34 6

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Reactivity Mouse (Murine)
(236), (220), (46), (3), (2), (1), (1)
Host Rat
(141), (127), (119), (18), (7), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL7R antibody is conjugated to PE
(29), (25), (24), (23), (19), (17), (11), (10), (9), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application ELISA (Detection)
(203), (186), (74), (67), (49), (26), (14), (12), (12), (11), (7), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN2662997) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone SB-199
Isotype IgG2b kappa

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling References for anti-IL7R antibody (ABIN2662997) Images back to top
Antigen
Alternative Name CD127 (IL7R Antibody Abstract)
Background CD127 is a 60-90 kD type I transmembrane glycoprotein, also known as IL-7 receptor α chain or IL-7Rα. It forms heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling References for anti-IL7R antibody (ABIN2662997) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details References for anti-IL7R antibody (ABIN2662997) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL7R antibody (ABIN2662997)

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling Images back to top
Background publications

Maeda, Baba, Nagai, Miyazaki, Malykhin, Nakamura, Kincade, Sakaguchi, Coggeshall: "IL-6 blocks a discrete early step in lymphopoiesis." in: Blood, Vol. 106, Issue 3, pp. 879-85, 2005

Huster, Busch, Schiemann, Linkemann, Kerksiek, Wagner, Busch: "Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 15, pp. 5610-5, 2004

Pillai, Torok-Storb, Iwata: "Expression and function of IL-7 receptors in marrow stromal cells." in: Leukemia & lymphoma, Vol. 45, Issue 12, pp. 2403-8, 2004

Diao, Winter, Chen, Cantin, Cattral: "Characterization of distinct conventional and plasmacytoid dendritic cell-committed precursors in murine bone marrow." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 3, pp. 1826-33, 2004

Kouro, Kumar, Kincade: "Relationships between early B- and NK-lineage lymphocyte precursors in bone marrow." in: Blood, Vol. 100, Issue 10, pp. 3672-80, 2002

He, Malek: "The structure and function of gamma c-dependent cytokines and receptors: regulation of T lymphocyte development and homeostasis." in: Critical reviews in immunology, Vol. 18, Issue 6, pp. 503-24, 1999

Yamashita, Oritani, Miyoshi, Wall, Bernfield, Kincade: "Syndecan-4 is expressed by B lineage lymphocytes and can transmit a signal for formation of dendritic processes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 10, pp. 5940-8, 1999

Sudo, Nishikawa, Ohno, Akiyama, Tamakoshi, Yoshida, Nishikawa: "Expression and function of the interleukin 7 receptor in murine lymphocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 19, pp. 9125-9, 1993

Morrissey, Goodwin, Nordan, Anderson, Grabstein, Cosman, Sims, Lupton, Acres, Reed: "Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells." in: The Journal of experimental medicine, Vol. 169, Issue 3, pp. 707-16, 1989

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN2662997) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 7 Receptor (IL7R) antibody (PE) (ABIN2662997) anti-Interleukin 7 Receptor (IL7R) antibody (PE)
Flow Cytometry (FACS) image for anti-Interleukin 7 Receptor (IL7R) antibody (PE) (ABIN2662997) anti-Interleukin 7 Receptor (IL7R) antibody (PE) (Image 2)