anti-Mouse (Murine) Leptin Receptor antibody for ELISA (Detection)

Recommended Leptin Receptor Antibody (supplied by: Log in to see )

Antigen
Leptin Receptor (LEPR) Antibodies
  • CD295
  • LEP-R
  • LEPRD
  • OB-R
  • OBR
  • obr
  • cd295
  • ob-rb
  • Fa
  • LEPROT
  • Leprb
  • Modb1
  • OB-RGRP
  • Obr
  • db
  • diabetes
  • obese-like
  • obl
  • ObRb
  • Ob-R
  • Ob-RM
  • lepr
  • leptin receptor
  • leptin receptor S homeolog
  • LEPR
  • lepr
  • Lepr
  • lepr.S
Epitope
AA 20-839
22
20
16
15
14
12
10
8
6
5
5
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
241
103
67
15
7
4
3
1
1
1
1
1
Host
Goat
167
71
25
17
2
1
Clonality
Polyclonal
Conjugate
This Leptin Receptor antibody is conjugated to Biotin
13
11
11
8
7
7
7
5
5
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
Application
ELISA (Detection), Flow Cytometry (FACS), Western Blotting (WB)
183
114
90
55
41
40
10
7
6
5
5
4
2
Supplier
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Catalog No. ABIN4899540
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General

Antigen Leptin Receptor (LEPR) Antibodies
Epitope AA 20-839
(22), (20), (16), (15), (14), (12), (10), (8), (6), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(241), (103), (67), (15), (7), (4), (3), (1), (1), (1), (1), (1)
Host Goat
(167), (71), (25), (17), (2), (1)
Clonality
Polyclonal
Conjugate This Leptin Receptor antibody is conjugated to Biotin
(13), (11), (11), (8), (7), (7), (7), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA (Detection), Flow Cytometry (FACS), Western Blotting (WB)
(183), (114), (90), (55), (41), (40), (10), (7), (6), (5), (5), (4), (2)
Pubmed 5 references available
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Product Details anti-Leptin Receptor Antibody

Target Details Leptin Receptor Application Details Handling References for anti-Leptin Receptor antibody (ABIN4899540) Images
Specificity Detects mouse Leptin R in ELISAs and Western blots.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Leptin R, Ala20-Gly839, Accession # Q3US58
Isotype IgG
Plasmids, Primers & others

Target Details Leptin Receptor

Product Details anti-Leptin Receptor Antibody Application Details Handling References for anti-Leptin Receptor antibody (ABIN4899540) Images back to top
Antigen
Alternative Name Leptin R (LEPR Antibody Abstract)
Background Alternative Names: B219, CD295, CD295 antigen, DB, DKFZp686B1731, huB219, LEPR, LEP-R, leptin receptor, LeptinR, OB R, OB receptor, OB-R, OBRCD295
Gene ID 3953
UniProt Q3US58
Pathways JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour

Application Details

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Handling References for anti-Leptin Receptor antibody (ABIN4899540) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
ELISA Detection (Matched Antibody Pair) 0.1-0.4 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Application Details References for anti-Leptin Receptor antibody (ABIN4899540) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-Leptin Receptor antibody (ABIN4899540)

Product Details anti-Leptin Receptor Antibody Target Details Leptin Receptor Application Details Handling Images back to top
Product cited in:

Lu, Xie, Wu, Shen, Collins, Chen, Kang, Luo, Zou, Huang, Amatruda, Slone, Winick, Scherer, Zhang: "Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation." in: Nature medicine, Vol. 23, Issue 1, pp. 79-90, 2017 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Farr, Fraser, Wang, Jaehn, Ogrodnik, Weivoda, Drake, Tchkonia, LeBrasseur, Kirkland, Bonewald, Pignolo, Monroe, Khosla: "Identification of Senescent Cells in the Bone Microenvironment." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1920-1929, 2016 Method employed by authors: Cell Sorting (CS), Cell Sorting (CS) (Sample species: Mouse (Murine)).

Garcin, Paul, Staufenbiel, Bordat, Van der Heyden, Wilmes, Cartron, Apparailly, De Koker, Piehler, Tavernier, Uzé: "High efficiency cell-specific targeting of cytokine activity." in: Nature communications, Vol. 5, pp. 3016, 2015 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Marie, Verkerke, Paul, Mackey, Petri: "Leptin protects host cells from Entamoeba histolytica cytotoxicity by a STAT3-dependent mechanism." in: Infection and immunity, Vol. 80, Issue 5, pp. 1934-43, 2012 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Mouse (Murine)).

Gruver, Ventevogel, Sempowski: "Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution." in: The Journal of endocrinology, Vol. 203, Issue 1, pp. 75-85, 2009 Method employed by authors: Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Sample species: Mouse (Murine)).