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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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4.751972 | ABIN5515079 | WB | Rabbit | Middle Region | Log in to see | Polyclonal | 0 | |||
1 | ABIN1926795 | WB | Rabbit | AA 254-303 | Log in to see | Polyclonal | 0 | |||
-12.75825 | ABIN4347620 | FACS IHC (fro) IHC (p) WB | DyLight 405 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347618 | FACS IHC (fro) IHC (p) WB | DyLight 350 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347622 | FACS ICC IF IHC IHC (fro) IHC (p) IP WB | PerCP | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347628 | FACS IHC (fro) IHC (p) WB | DyLight 488 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347632 | FACS IHC (fro) IHC (p) WB | DyLight 680 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347634 | FACS IHC (fro) IHC (p) WB | Alexa Fluor 405 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347636 | FACS IHC (fro) IHC (p) WB | Alexa Fluor 488 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347638 | FACS IHC (fro) IHC (p) WB | Alexa Fluor 647 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347640 | FACS IHC (fro) IHC (p) WB | Alexa Fluor 700 | Mouse | IgG1 | Log in to see | U5 | 0 | ||
-12.75825 | ABIN4347626 | FACS IHC (fro) IHC (p) WB | DyLight 755 | Mouse | IgG1 | Log in to see | U5 | 0 |
General |
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Antigen | Prolactin Receptor (PRLR) Antibodies |
Reactivity | Cow (Bovine), Hamster, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine) Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This Prolactin Receptor antibody is un-conjugated Alternatives |
Application |
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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10 references available |
Supplier | Log in to see |
Product Details anti-Prolactin Receptor AntibodyTarget Details Prolactin Receptor Application Details Handling References for anti-Prolactin Receptor antibody (ABIN152720) Images |
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Purification | Protein G purified |
Immunogen | Purified rat liver PRL receptor. |
Clone | U5 |
Isotype | IgG1 |
Plasmids, Primers & others | |
Target Details Prolactin ReceptorProduct Details anti-Prolactin Receptor Antibody Application Details Handling References for anti-Prolactin Receptor antibody (ABIN152720) Images back to top |
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Antigen | |
Alternative Name | Prolactin R (PRLR Antibody Abstract) |
Background | Gene Symbol: PRLR |
Gene ID | 5618 |
UniProt | P16471 |
Pathways | JAK-STAT Signaling, Response to Growth Hormone Stimulus |
Application DetailsProduct Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Handling References for anti-Prolactin Receptor antibody (ABIN152720) Images back to top |
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Application Notes | Western Blot 1 μg/mL, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Paraffin 1:10 - 1:500, Immunohistochemistry-Frozen 1:10 - 1:500, Immunofluorescence 1:20, Immunocytochemistry 5 μg/mLMay be useful in IHC, IP, and WB. WB: Detects an approx. 40 kDa and 100 kDa protein representing both the short and long forms of the PRL receptor, respectively, in various tissues. IHC: Staining of PRL receptor in rat Islets of Langerhans with NB 300-561 results in a staining pattern consistent with cytoplasmic vesicle staining. NB 300-561, after biotinylation, has been used to detect human lymphocyte PRL receptor by Flow Cytometry. NB 300-561 does not inhibit the interaction of prolactin with the receptor. |
Comment |
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo. |
Restrictions | For Research Use only |
HandlingProduct Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details References for anti-Prolactin Receptor antibody (ABIN152720) Images back to top |
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Format | Lyophilized |
Reconstitution | Reconstitute with 0.1 mL PBS. |
Buffer |
No buffer Buffer contains: 0.05 % Sodium Azide |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid freeze-thaw cycles |
Storage | -20 °C |
Storage Comment | Store at -20°C. Avoid freeze-thaw cycles. |
References for anti-Prolactin Receptor antibody (ABIN152720)Product Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Handling Images back to top |
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Product cited in: |
Perrot-Applanat, Gualillo, Buteau, Edery, Kelly: "Internalization of prolactin receptor and prolactin in transfected cells does not involve nuclear translocation." in: Journal of cell science, Vol. 110 ( Pt 9), pp. 1123-32, 1997 Royster, Driscoll, Kelly, Freemark: "The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation." in: Endocrinology, Vol. 136, Issue 9, pp. 3892-900, 1995 Sorenson, Stout: "Prolactin receptors and JAK2 in islets of Langerhans: an immunohistochemical analysis." in: Endocrinology, Vol. 136, Issue 9, pp. 4092-8, 1995 Rui, Lebrun, Kirken, Kelly, Farrar: "JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization." in: Endocrinology, Vol. 135, Issue 4, pp. 1299-306, 1994 Dardenne, de Moraes, Kelly, Gagnerault: "Prolactin receptor expression in human hematopoietic tissues analyzed by flow cytofluorometry." in: Endocrinology, Vol. 134, Issue 5, pp. 2108-14, 1994 Gagnerault, Touraine, Savino, Kelly, Dardenne: "Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5673-81, 1993 Rozakis-Adcock, Kelly: "Mutational analysis of the ligand-binding domain of the prolactin receptor." in: The Journal of biological chemistry, Vol. 266, Issue 25, pp. 16472-7, 1991 Dardenne, Kelly, Bach, Savino: "Identification and functional activity of prolactin receptors in thymic epithelial cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 21, pp. 9700-4, 1991 Okamura, Zachwieja, Raguet, Kelly: "Characterization and applications of monoclonal antibodies to the prolactin receptor." in: Endocrinology, Vol. 124, Issue 5, pp. 2499-508, 1989 Katoh, Raguet, Zachwieja, Djiane, Kelly: "Hepatic prolactin receptors in the rat: characterization using monoclonal antireceptor antibodies." in: Endocrinology, Vol. 120, Issue 2, pp. 739-49, 1987 |
ImagesProduct Details anti-Prolactin Receptor Antibody Target Details Prolactin Receptor Application Details Handling References for anti-Prolactin Receptor antibody (ABIN152720) back to top |
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