anti-Rat (Rattus) PTPN6 antibody for Immunocytochemistry

Recommended PTPN6 Antibody (supplied by: Log in to see )

Antigen
Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
  • HCPH
  • HPTP1C
  • PTP-1C
  • SH-PTP1
  • SHP-1
  • SHP-1L
  • SHP1
  • DRPLA
  • Hcph
  • Ptp1C
  • me
  • motheaten
  • Ptph6
  • Shp-1
  • fj22f05
  • wu:fj22f05
  • zgc:55501
  • ptpn6
  • protein tyrosine phosphatase, non-receptor type 6
  • protein tyrosine phosphatase, non-receptor type 6 L homeolog
  • PTPN6
  • Ptpn6
  • ptpn6
  • ptpn6.L
Epitope
pTyr536
36
26
15
10
9
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
231
100
91
5
4
2
2
2
1
1
1
1
1
Host
Rabbit
156
41
35
Clonality
Polyclonal
Conjugate
This PTPN6 antibody is un-conjugated
9
9
8
3
3
3
3
3
3
3
3
3
3
3
3
3
2
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
169
103
72
40
39
36
21
11
8
8
7
5
2
1
Supplier
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Catalog No. ABIN6255949
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13 ABIN6265073 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
10 ABIN6264520 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
Epitope pTyr536
(36), (26), (15), (10), (9), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(231), (100), (91), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(156), (41), (35)
Clonality
Polyclonal
Conjugate This PTPN6 antibody is un-conjugated
(9), (9), (8), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(169), (103), (72), (40), (39), (36), (21), (11), (8), (8), (7), (5), (2), (1)
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Product Details anti-PTPN6 Antibody

Target Details PTPN6 Application Details Handling Images
Specificity Phospho-SHP-1 (Tyr536) Antibody detects endogenous levels of SHP-1 only when phosphorylated at Tyrosine 536
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyrosine 536
Isotype IgG
Plasmids, Primers & others

Target Details PTPN6

Product Details anti-PTPN6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SHP-1 (PTPN6 Antibody Abstract)
Background

Description: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Gene: PTPN6

Molecular Weight 67kDa
Gene ID 5777
UniProt P29350
Pathways JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-PTPN6 Antibody Target Details PTPN6 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling back to top
Supplier Images
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody (ABIN6255949) ABIN6267455 staining RAW264.7 by IF/ICC. The sample were fixed with PFA and permeabil...
Western Blotting (WB) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody (ABIN6255949) Western blot analysis of SHP-1 phosphorylation expression in EGF treated RAW264.7 who...
Immunohistochemistry (IHC) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody (ABIN6255949) ABIN6267455 at 1/100 staining human bone tissue sections by IHC-P. The tissue was for...
Western Blotting (WB) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody (ABIN6255949) Western blot analysis of Phospho-SHP-1 (Tyr536) expression in various lysates