anti-Rat (Rattus) Serotonin Receptor 2B antibody for Western Blotting

Recommended Serotonin Receptor 2B Antibody (supplied by: Log in to see )

Antigen
Serotonin Receptor 2B (HTR2B) Antibodies
  • 5-HT2B
  • 5HT2B
  • 5htr2b
  • HTR2B
  • 5ht2b
  • zgc:194094
  • zgc:194119
  • AJ012488
  • AV377389
  • 5-HT(2B)
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • 5-hydroxytryptamine (serotonin) receptor 2B
  • HTR2B
  • htr2b
  • Htr2b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
105
24
22
3
2
2
2
2
1
1
Host
Rabbit
103
4
Clonality
Polyclonal
Conjugate
This Serotonin Receptor 2B antibody is un-conjugated
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
59
33
29
27
23
20
5
5
4
1
Supplier
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Catalog No. ABIN6262416
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.802364 ABIN5530221 IHC (p) WB Rabbit Ig Fraction AA 408-435, C-Term Log in to see Polyclonal 0
10.802364 ABIN2976164 IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal 0
7.8023643 ABIN5962832 IHC WB Rabbit IgG Log in to see Polyclonal 0
7.8023643 ABIN2427711 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
4.8023643 ABIN3042730 WB Rabbit IgG AA 446-478, C-Term Log in to see Polyclonal 0
4.8023643 ABIN1876871 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2881212 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN731147 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal 0
1 ABIN731140 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN731138 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4949959 WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Serotonin Receptor 2B (HTR2B) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(105), (24), (22), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(103), (4)
Clonality
Polyclonal
Conjugate This Serotonin Receptor 2B antibody is un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(59), (33), (29), (27), (23), (20), (5), (5), (4), (1)
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Product Details anti-Serotonin Receptor 2B Antibody

Target Details Serotonin Receptor 2B Application Details Handling Images
Specificity HTR2B Antibody detects endogenous levels of total HTR2B
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human HTR2B
Isotype IgG
Plasmids, Primers & others

Target Details Serotonin Receptor 2B

Product Details anti-Serotonin Receptor 2B Antibody Application Details Handling Images back to top
Antigen
Alternative Name HTR2B (HTR2B Antibody Abstract)
Background

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:8882600, PubMed:18703043, PubMed:23519210). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances (PubMed:8143856, PubMed:7926008, PubMed:8078486, PubMed:12970106, PubMed:18703043, PubMed:23519210, PubMed:23519215, PubMed:24357322, PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:8143856, PubMed:8078486, PubMed:8882600, PubMed:23519215, PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:23519215, PubMed:28129538). Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores (PubMed:8143856, PubMed:8078486, PubMed:8882600, PubMed:18703043, PubMed:23519215, PubMed:28129538). Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain (By similarity). Plays a role in the regulation of behavior, including impulsive behavior (PubMed:21179162). Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine (By similarity).

Gene: HTR2B

Molecular Weight 54kDa
Gene ID 3357
UniProt P41595
Pathways JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-Serotonin Receptor 2B Antibody Target Details Serotonin Receptor 2B Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) antibody (ABIN6262416) Western blot analysis of Mouse liver tissue lysates, using HTR2B Antibody. The lane o...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Serotonin Receptor 2B (HTR2B) antibody (ABIN6262416) ABIN6277692 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized...
Immunohistochemistry (IHC) image for anti-Serotonin Receptor 2B (HTR2B) antibody (ABIN6262416) ABIN6277692 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was form...