anti-Mouse (Murine) SOCS1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS1 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
  • socs1
  • zgc:91868
  • jab
  • cis1
  • ssi1
  • tip3
  • cish1
  • ssi-1
  • socs-1
  • SOCS1
  • LOC100228306
  • socs1b
  • CIS1
  • CISH1
  • JAB
  • SOCS-1
  • SSI-1
  • SSI1
  • TIP3
  • Cish1
  • Cish7
  • Socs-1
  • suppressor of cytokine signaling 1a
  • suppressor of cytokine signaling 1
  • suppressor of cytokine signaling 1 L homeolog
  • socs1a
  • socs1
  • SOCS1
  • socs1.L
  • Socs1
Epitope
C-Term
53
21
15
6
3
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
166
97
78
10
8
7
5
4
3
3
3
Host
Rabbit
150
19
11
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
11
7
6
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
154
62
50
29
14
13
11
8
6
6
5
2
Supplier
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Catalog No. ABIN1109093
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.982011 ABIN451850 ELISA IHC (p) WB Rabbit C-Term Log in to see Polyclonal 1
12.982011 ABIN343903 ELISA IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
12.982011 ABIN263007 IHC (p) IHC ELISA WB Goat C-Term Log in to see Polyclonal 1
12.982011 ABIN725135 IF (p) IHC (p) WB Rabbit IgG AA 160-211 Log in to see Polyclonal 0
1 ABIN2854825 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN652738 FACS IF IHC (p) WB Rabbit Ig Fraction AA 35-66, N-Term Log in to see Polyclonal 2
1 ABIN203422 IHC IHC (p) WB Rabbit IgG AA 21-70 Log in to see Polyclonal 0
1 ABIN5552634 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal 0
1 ABIN1492941 IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN372904 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN600215 ICC IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN1739505 IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN725144 IHC (p) WB HRP Rabbit IgG AA 160-211 Log in to see Polyclonal 0
1 ABIN725137 IHC (p) WB Biotin Rabbit IgG AA 160-211 Log in to see Polyclonal 0
1 ABIN1809514 FACS IF IHC IHC (p) WB Rabbit AA 35-66 Log in to see Polyclonal 0
1 ABIN5957633 ELISA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4355046 IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN3029041 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN2964271 IHC (p) WB Mouse IgG1 AA 2-78 Log in to see 4H1 0
1 ABIN2572144 IHC IHC (p) WB Mouse IgG1 Log in to see 4H1 0

General

Antigen Suppressor of Cytokine Signaling 1 (SOCS1) Antibodies
Epitope C-Term
(53), (21), (15), (6), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(166), (97), (78), (10), (8), (7), (5), (4), (3), (3), (3)
Host Rabbit
(150), (19), (11)
Clonality
Polyclonal
Conjugate This SOCS1 antibody is un-conjugated
(11), (7), (6), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(154), (62), (50), (29), (14), (13), (11), (8), (6), (6), (5), (2)
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Product Details anti-SOCS1 Antibody

Target Details SOCS1 Application Details Handling Images
Specificity This antibody detects SOCS1 / JAB (C-term). No cross reactivity with other proteins.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Immunogen affinity purified
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1 .Remarks: Sequence is identical to the related mouse and rat sequence.
Isotype IgG
Plasmids, Primers & others

Target Details SOCS1

Product Details anti-SOCS1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SOCS1 (SOCS1 Antibody Abstract)
Background Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
Gene ID 8651
NCBI Accession NP_003736
UniProt O15524
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling, Response to Growth Hormone Stimulus

Application Details

Product Details anti-SOCS1 Antibody Target Details SOCS1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Images back to top
Reconstitution 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-SOCS1 Antibody Target Details SOCS1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody (ABIN1109093) Immunohistochemical analysis of paraffin-embedded rat tissue sections (lung), stainin...