anti-Mouse (Murine) STAT1 antibody for Immunofluorescence
Recommended STAT1 Antibody
- Antigen
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Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
show synonyms for this antigen- CANDF7
- ISGF-3
- STAT91
- 2010005J02Rik
- AA408197
- XStat1
- STAT4
- DD6G4-4
- STAT
- STAT1
- dZ182H3.3
- si:by134g18.2
- si:by51f19.1
- si:dz182h3.3
- si:dz199m19.1
- si:dz73o4.2
- stat1
- signal transducer and activator of transcription 1
- signal transducer and activator of transcription 1 L homeolog
- signal transducer and activator of transcription 1, 91kDa
- signal transducer and activator of transcription 4
- signal transducer and activator of transcription 1a
- STAT1
- Stat1
- stat1.L
- stat4
- stat1a
- Epitope
-
pSer727
Alternatives - Reactivity
-
Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This STAT1 antibody is un-conjugated
Alternatives - Application
-
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives - Options
Available images
Plus shipping costs $45.00
| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|
| 14.593626 | ABIN2705254 | IC IF IP IHC WB | Rabbit | C-Term, pSer727 | Polyclonal | 0 | |||
| 14.593626 | ABIN1870637 | IF IHC WB | Rabbit | IgG | pSer727 | Polyclonal | 0 | ||
| 14.593626 | ABIN2957762 | IC IF IP IHC WB | Rabbit | C-Term, pTyr701 | Polyclonal | 0 | |||
| 14.5 | ABIN6255991 | ELISA ICC IF IHC IP WB | Rabbit | IgG | pTyr701 | Polyclonal | 2 | ||
| 14.5 | ABIN6265311 | ELISA ICC IF IHC IP WB | Rabbit | IgG | Polyclonal | 2 | |||
| 13.448026 | ABIN1842362 | IF IHC WB | Rabbit | IgG | pSer727 | Polyclonal | 0 | ||
| 10 | ABIN6652217 | IF IHC (p) WB | Rabbit | pSer727 | Polyclonal | 4 | |||
| 10 | ABIN6265313 | ELISA ICC IF IHC WB | Rabbit | IgG | Polyclonal | 0 | |||
| 9.520277 | ABIN4356288 | ICC IF IHC IHC (p) WB | Rabbit | IgG | Polyclonal | 0 | |||
| 8.593626 | ABIN6290945 | IF WB | Rabbit | IgG | Polyclonal | 0 | |||
| 7 | ABIN303289 | IF IHC (p) IP WB | Rabbit | C-Term | Polyclonal | 0 | |||
| 7 | ABIN6579986 | IF IHC WB | Rabbit | IgG | pSer727 | Polyclonal | 0 | ||
| 5.5 | ABIN362170 | IF IHC WB | Rabbit | IgG | pSer727 | Polyclonal | 5 | ||
| 4.926651 | ABIN5947757 | FACS ICC IF IHC IHC (p) IP WB | Rabbit | IgG | C-Term | SD20-75 | 0 | ||
| 4 | ABIN5957642 | ELISA IF IHC (p) WB | Rabbit | IgG | pTyr701 | Polyclonal | 0 | ||
| 4 | ABIN5957648 | ELISA IF IHC (p) WB | Rabbit | IgG | Ser727 | Polyclonal | 0 | ||
| 4 | ABIN6714596 | IF IHC IP WB | Rabbit | Polyclonal | 0 | ||||
| 1 | ABIN5555267 | EIA IF IP WB | Rabbit | IgG | C-Term | Polyclonal | 0 | ||
| 1 | ABIN6760816 | IF IHC WB | Rabbit | IgG | pSer727 | Polyclonal | 0 | ||
| 1 | ABIN2628793 | ICC IF IHC IHC (p) IP WB | Rabbit | pSer727 | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies |
| Epitope | pSer727 Alternatives |
| Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This STAT1 antibody is un-conjugated Alternatives |
| Application |
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
|
|
1 reference available |
| Supplier | |
Product Details anti-STAT1 AntibodyTarget Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN6256410) Images |
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| Specificity | Phospho-STAT1 (Ser727) Antibody detects endogenous levels of STAT1 only when phosphorylated at Serine 727 |
| Cross-Reactivity | Human, Mouse (Murine), Rat (Rattus) |
| Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
| Immunogen | A synthesized peptide derived from human STAT1 around the phosphorylation site of Serine 727 |
| Isotype | IgG |
| Plasmids, Primers & others | |
Target Details STAT1Product Details anti-STAT1 Antibody Application Details Handling References for anti-STAT1 antibody (ABIN6256410) Images back to top |
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| Antigen | |
| Alternative Name | STAT1 (STAT1 Antibody Abstract) |
| Background |
Description: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus (PubMed:28753426). ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated (PubMed:26479788). It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Gene: STAT1 |
| Molecular Weight | 91kDa |
| Gene ID | 6772 |
| UniProt | P42224 |
| Pathways | JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events |
Application DetailsProduct Details anti-STAT1 Antibody Target Details STAT1 Handling References for anti-STAT1 antibody (ABIN6256410) Images back to top |
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| Application Notes | WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-STAT1 Antibody Target Details STAT1 Application Details References for anti-STAT1 antibody (ABIN6256410) Images back to top |
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| Format | Liquid |
| Concentration | 1 mg/mL |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Store at -20 °C.Stable for 12 months from date of receipt |
| Expiry Date | 12 months |
References for anti-STAT1 antibody (ABIN6256410)Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top |
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| Product cited in: |
Wu, Chen, Jing, Gu, Mei, Yao, Zhou, Yang, Sun, Wang, Hu, Wüthrich, Mei: "The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1." in: American journal of physiology. Renal physiology, Vol. 310, Issue 11, pp. F1284-94, 2017 |
ImagesProduct Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN6256410) back to top |
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| Supplier Images |
Western blot analysis of STAT1 phosphorylation expression in Jurkat whole cell lysate...
ABIN6267508 at 1/200 staining Human lung cancer tissue sections by IHC-P. The tissue ...
ABIN6267508 at 1/200 staining Human bladder cancer tissue sections by IHC-P. The tiss...
ABIN6267508 at 1/200 staining Mouse testis tissue sections by IHC-P. The tissue was f...
ABIN6267508 at 1/200 staining Mouse lung tissue sections by IHC-P. The tissue was for...
ABIN6267508 at 1/200 staining Rat lung tissue sections by IHC-P. The tissue was forma...
ABIN6267508 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized...
ABIN6267508 staining MCF7 by IF/ICC. The sample were fixed with PFA and permeabilized...
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