anti-Mouse (Murine) STAT1 antibody for Immunofluorescence

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • CANDF7
  • ISGF-3
  • STAT91
  • 2010005J02Rik
  • AA408197
  • XStat1
  • STAT4
  • DD6G4-4
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • stat1
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 1 L homeolog
  • signal transducer and activator of transcription 1, 91kDa
  • signal transducer and activator of transcription 4
  • signal transducer and activator of transcription 1a
  • STAT1
  • Stat1
  • stat1.L
  • stat4
  • stat1a
Epitope
pSer727
103
83
54
20
18
17
15
9
8
8
8
7
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
566
314
258
35
26
23
20
19
12
12
9
8
5
4
3
2
2
2
1
1
1
1
1
Host
Rabbit
449
138
9
2
1
1
Clonality
Polyclonal
Conjugate
This STAT1 antibody is un-conjugated
16
14
11
11
10
10
7
5
5
5
4
4
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
483
231
167
113
111
56
52
28
28
12
9
7
6
5
3
2
1
1
1
Options
Supplier
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Supplier Product No.
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Pubmed
1 reference available

Available images

Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410)
Catalog No. ABIN6256410
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.648714 ABIN2705254 IC IF IP IHC WB Rabbit C-Term, pSer727 Log in to see Polyclonal 0
14.648714 ABIN1870637 IF IHC WB Rabbit IgG pSer727 Log in to see Polyclonal 0
14.648714 ABIN2957762 IC IF IP IHC WB Rabbit C-Term, pTyr701 Log in to see Polyclonal 0
14.5 ABIN6255991 ELISA ICC IF IHC IP WB Rabbit IgG pTyr701 Log in to see Polyclonal 2
14.5 ABIN6265311 ELISA ICC IF IHC IP WB Rabbit IgG Log in to see Polyclonal 2
11.814945 ABIN1842362 IF IHC WB Rabbit IgG pSer727 Log in to see Polyclonal 0
10 ABIN6652217 IF IHC (p) WB Rabbit pSer727 Log in to see Polyclonal 4
10 ABIN6265313 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
9.819754 ABIN4356288 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
8.648714 ABIN6290945 IF WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN303289 IF IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal 0
7 ABIN6579986 IF IHC WB Rabbit IgG pSer727 Log in to see Polyclonal 0
5.5 ABIN362170 IF IHC WB Rabbit IgG pSer727 Log in to see Polyclonal 5
5.1710396 ABIN5947757 FACS ICC IF IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see SD20-75 0
4 ABIN5957642 ELISA IF IHC (p) WB Rabbit IgG pTyr701 Log in to see Polyclonal 0
4 ABIN5957648 ELISA IF IHC (p) WB Rabbit IgG Ser727 Log in to see Polyclonal 0
4 ABIN6714596 IF IHC IP WB Rabbit Log in to see Polyclonal 0
1 ABIN5555267 EIA IF IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN2882786 IF IHC WB Rabbit IgG pSer727 Log in to see Polyclonal 0
1 ABIN2628793 ICC IF IHC IHC (p) IP WB Rabbit pSer727 Log in to see Polyclonal 0

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Epitope pSer727
(103), (83), (54), (20), (18), (17), (15), (9), (8), (8), (8), (7), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(566), (314), (258), (35), (26), (23), (20), (19), (12), (12), (9), (8), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(449), (138), (9), (2), (1), (1)
Clonality
Polyclonal
Conjugate This STAT1 antibody is un-conjugated
(16), (14), (11), (11), (10), (10), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(483), (231), (167), (113), (111), (56), (52), (28), (28), (12), (9), (7), (6), (5), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN6256410) Images
Specificity Phospho-STAT1 (Ser727) Antibody detects endogenous levels of STAT1 only when phosphorylated at Serine 727
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human STAT1 around the phosphorylation site of Serine 727
Isotype IgG
Plasmids, Primers & others

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling References for anti-STAT1 antibody (ABIN6256410) Images back to top
Antigen
Alternative Name STAT1 (STAT1 Antibody Abstract)
Background

Description: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus (PubMed:28753426). ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated (PubMed:26479788). It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Gene: STAT1
Molecular Weight 91kDa
Gene ID 6772
UniProt P42224
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling References for anti-STAT1 antibody (ABIN6256410) Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details References for anti-STAT1 antibody (ABIN6256410) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

References for anti-STAT1 antibody (ABIN6256410)

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top
Product cited in:

Wu, Chen, Jing, Gu, Mei, Yao, Zhou, Yang, Sun, Wang, Hu, Wüthrich, Mei: "The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1." in: American journal of physiology. Renal physiology, Vol. 310, Issue 11, pp. F1284-94, 2017

Images

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN6256410) back to top
Supplier Images
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) Western blot analysis of STAT1 phosphorylation expression in Jurkat whole cell lysate...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 at 1/200 staining Human lung cancer tissue sections by IHC-P. The tissue ...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 at 1/200 staining Human bladder cancer tissue sections by IHC-P. The tiss...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 at 1/200 staining Mouse testis tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 at 1/200 staining Mouse lung tissue sections by IHC-P. The tissue was for...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 at 1/200 staining Rat lung tissue sections by IHC-P. The tissue was forma...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody (ABIN6256410) ABIN6267508 staining MCF7 by IF/ICC. The sample were fixed with PFA and permeabilized...