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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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9.064541 | ABIN2705256 | IP IHC WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN2705254 | IC IF IP IHC WB | Rabbit | C-Term, pSer727 | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN1533008 | ELISA IHC IP WB | Rabbit | IgG | AA 668-717 | Log in to see | Polyclonal | 2 | ||
9.064541 | ABIN1531973 | IHC ELISA WB | Rabbit | IgG | AA 694-743, pSer727 | Log in to see | Polyclonal | 1 | ||
9.064541 | ABIN1531974 | ELISA IHC IP WB | Rabbit | IgG | AA 668-717, pTyr701 | Log in to see | Polyclonal | 1 | ||
9.064541 | ABIN1533007 | IHC ELISA WB | Rabbit | IgG | AA 694-743 | Log in to see | Polyclonal | 0 | ||
9.064541 | ABIN408486 | IHC (p) IP IHC WB | Rabbit | IgG | pTyr701 | Log in to see | Polyclonal | 0 | ||
9.064541 | ABIN1870637 | IF IHC WB | Rabbit | IgG | pSer727 | Log in to see | Polyclonal | 0 | ||
9.064541 | ABIN2469995 | IP IHC WB | Mouse | IgG2b | AA 721-733 | Log in to see | SM1 | 0 | ||
9.064541 | ABIN2957762 | IC IF IP IHC WB | Rabbit | C-Term, pTyr701 | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN2469752 | IHC WB | Mouse | IgG1 | Log in to see | SAT-84 | 0 | |||
9.064541 | ABIN3181580 | IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN2427589 | IHC ELISA | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN1847530 | IHC ELISA WB | Rabbit | C-Term, pSer727 | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN1847532 | IP IHC ELISA WB | Rabbit | C-Term, pTyr701 | Log in to see | Polyclonal | 0 | |||
9.064541 | ABIN1848154 | IP IHC ELISA WB | Rabbit | C-Term, Tyr701 | Log in to see | Polyclonal | 0 | |||
1 | ABIN2780844 | IHC WB | Rabbit | C-Term | Log in to see | Polyclonal | 1 | |||
1 | ABIN967759 | IF IP IHC WB | Mouse | IgG1 | AA 1-194 | Log in to see | 1-Stat1 | 5 | ||
1 | ABIN269146 | IHC (p) IP IHC WB | Mouse | IgG2b | AA 721-733 | Log in to see | SM1 | 2 | ||
1 | ABIN967758 | IF IP IHC WB | Mouse | IgG1 | AA 1-194 | Log in to see | 1-Stat1 | 5 |
General |
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Antigen | Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies |
Epitope | N-Term Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish (Danio rerio) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This STAT1 antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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2 references available |
Supplier | Log in to see |
Product Details anti-STAT1 AntibodyTarget Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN2780843) Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN984525 |
Sequence | MSQWYELQQL DSKFLEQVHQ LYDDSFPMEI RQYLAQWLEK QDWEHAANDV |
Predicted Reactivity | Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86% |
Characteristics | This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot and immunohistochemistry. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1 |
Target Details STAT1Product Details anti-STAT1 Antibody Application Details Handling References for anti-STAT1 antibody (ABIN2780843) Images back to top |
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Antigen | |
Alternative Name | STAT1 (STAT1 Antibody Abstract) |
Background |
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. Alias Symbols: DKFZp686B04100, ISGF-3, STAT91, CANDF7 Protein Interaction Partner: HUWE1, ISG15, PIAS1, UBC, STAT1, EIF1AD, OTUD4, LMO2, GNB2, DTX3L, EGFR, NAA15, SNX6, CAND1, VPS29, GSPT2, JMJD6, RTF1, HSPA4L, ATG7, YAP1, PAWR, KARS, IDE, CTTN, VPS26A, HIRIP3, NAA10, TSNAX, TBCD, SNX2, SNX1, SHMT2, SHMT1, SARS, ATP6V1C1, APEH, USP13, E Protein Size: 750 |
Molecular Weight | 87 kDa |
Gene ID | 6772 |
NCBI Accession | NM_007315, NP_009330 |
UniProt | P42224 |
Pathways | JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events |
Application DetailsProduct Details anti-STAT1 Antibody Target Details STAT1 Handling References for anti-STAT1 antibody (ABIN2780843) Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 750 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-STAT1 Antibody Target Details STAT1 Application Details References for anti-STAT1 antibody (ABIN2780843) Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-STAT1 antibody (ABIN2780843)Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top |
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Product cited in: |
Deng, Chen, Li, Yuan, Li, Ke, Wang, Wu, Luo: "Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, 2015 |
Background publications |
Battle, Lynch, Frank: "Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis." in: Cancer research, Vol. 66, Issue 7, pp. 3649-57, 2006 |
ImagesProduct Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling References for anti-STAT1 antibody (ABIN2780843) back to top |
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Supplier Images |