anti-Human STAT3 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
  • signal transducer and activator of transcription 3
  • signal transduction and activation of transcription 3
  • signal transducer and activator of transcription 3, gene 1 L homeolog
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • STAT3
  • stat3
  • Stat3
  • stat3.1.L
Epitope
AA 685-725, pTyr705
126
102
72
18
15
15
15
14
12
10
7
7
5
5
5
5
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
630
360
288
42
38
32
31
14
11
10
7
7
5
5
4
3
3
1
1
1
1
1
Host
Rabbit
499
133
35
4
2
1
Clonality
Polyclonal
Conjugate
This STAT3 antibody is un-conjugated
27
23
19
15
12
11
7
5
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
588
284
256
104
98
92
58
55
26
24
12
10
9
8
5
5
3
3
2
2
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN732638
$ 340.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN738261 FACS IF (p) IHC (p) WB Rabbit IgG AA 260-310 Log in to see Polyclonal 3
1 ABIN732645 FACS IF (p) FITC Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 1
1 ABIN746198 IF (p) IHC (p) WB Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 2
1 ABIN880076 FACS IF (p) Alexa Fluor 647 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN876900 IF (p) Alexa Fluor 350 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN746204 IF (p) Cy7 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN732643 FACS IF (p) Cy5.5 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN732641 FACS IF (p) Cy3 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN732644 FACS IF (p) Cy7 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN732642 FACS IF (p) Cy5 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN746201 IF (p) Cy3 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN746202 IF (p) Cy5 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN746203 IF (p) Cy5.5 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN746205 IF (p) FITC Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN876899 IF (p) Alexa Fluor 647 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN876898 IF (p) Alexa Fluor 555 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN876901 IF (p) Alexa Fluor 488 Rabbit IgG AA 710-740, pSer727 Log in to see Polyclonal 0
1 ABIN880075 FACS IF (p) Alexa Fluor 488 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN880074 FACS IF (p) Alexa Fluor 350 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0
1 ABIN880077 FACS IF (p) Alexa Fluor 555 Rabbit IgG AA 685-725, pTyr705 Log in to see Polyclonal 0

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Epitope AA 685-725, pTyr705
(126), (102), (72), (18), (15), (15), (15), (14), (12), (10), (7), (7), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(630), (360), (288), (42), (38), (32), (31), (14), (11), (10), (7), (7), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1)
Host Rabbit
(499), (133), (35), (4), (2), (1)
Clonality
Polyclonal
Conjugate This STAT3 antibody is un-conjugated
(27), (23), (19), (15), (12), (11), (7), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(588), (284), (256), (104), (98), (92), (58), (55), (26), (24), (12), (10), (9), (8), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
Supplier Log in to see

Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling References for anti-STAT3 antibody (ABIN732638) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705
Isotype IgG
Plasmids, Primers & others

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling References for anti-STAT3 antibody (ABIN732638) Images back to top
Antigen
Alternative Name Stat3 (STAT3 Antibody Abstract)
Background

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Subcellular location: Cytoplasm, Nucleus

Synonyms: APRF, HIES, ADMIO, Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3

Gene ID 6774
UniProt P40763
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling References for anti-STAT3 antibody (ABIN732638) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details References for anti-STAT3 antibody (ABIN732638) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-STAT3 antibody (ABIN732638)

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling Images back to top
Product cited in:

Zhang, Zhang, Zuo, Wang, Zhang, Xu, Li, Chen: "JAK-STAT signaling regulation of chicken embryonic stem cell differentiation into male germ cells." in: In vitro cellular & developmental biology. Animal, Vol. 53, Issue 8, pp. 728-743, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Chicken).

Gao, Wang, Sun, Li, Wang, Yi, Wang: "Morusin shows potent antitumor activity for human hepatocellular carcinoma in vitro and in vivo through apoptosis induction and angiogenesis inhibition." in: Drug design, development and therapy, Vol. 11, pp. 1789-1802, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Lee, Lee, Kim, Kim, Yang, Jeong, Seong: "Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146463, 2016 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Mouse (Murine)).

Sur, Swier, Radwan, Agrawal: "Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147937, 2016 Method employed by authors: Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (Sample species: Pig (Porcine)). Further details: Sample: heart

Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." in: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, 2016

Yang, Sun, Sun, Qi: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, 2012 Method employed by authors: Western Blotting (WB) (Sample species: Pig (Porcine)).

Images

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling References for anti-STAT3 antibody (ABIN732638) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 685-725), (pTyr705) antibody (ABIN732638) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-phospho...
Flow Cytometry (FACS) image for anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 685-725), (pTyr705) antibody (ABIN732638) This image has been kindly submitted by Tübingen Ageing and Tumour Immunology Group (...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 685-725), (pTyr705) antibody (ABIN732638) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-STAT3 (T...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 685-725), (pTyr705) antibody (ABIN732638) Paraformaldehyde-fixed, paraffin embedded human stomach cancer tissue, Antigen retrie...