Anti-Measles Virus IgM (MV IgM) ELISA Kit

Catalog No. ABIN1326874

Product Details

Target: Anti-Measles Virus IgM (MV IgM)

Reactivity: Human

Detection Method: Colorimetric

Method Type: Competition ELISA

Application: ELISA

Purpose: Diluted patient serum (serum diluent contains sorbent to remove Rheumatoid Factor and human IgG interference) is added to wells coated with purified measles antigen. Measles IgM specific antibody, if present, binds to the antigen. All unbound materials are washed away and the enzyme conjugate is added to bind to the antibody-antigen complex, if present. Excess enzyme conjugate is washed off and substrate is added. The plate is incubated to allow the hydrolysis of the substrate by the enzyme. The intensity of the color generated is proportional to the amount of IgM specific antibody in the sample.

Sample Type: Serum

Analytical Method: Qualitative

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Target Details

Target: Anti-Measles Virus IgM (MV IgM)

Alternative Name: Measles IgM

Target Type: Antibody

Background: Measles is an acute, highly contagious viral disease. Although measles is usually considered a childhood disease, it can be contracted at any age. Measles is spread by direct contact with nasal or throat secretions of infected people or, less frequently, by airborne transmission. Measles symptoms generally appear in two stages. In the first stage, the inidual may have a runny nose, cough and a slight fever. The second stage begins on the third to seventh day and consists of high fever and red blotchy rash lasting four to seven days. The rash usually begins on the face and then spreads over the entire body. Symptoms usually appear in 10-12 days, although they may occur between 8-13 days after exposure. The presence of IgG antibody to measles virus is indicative of previous exposure or vaccination. In iniduals with acute measles, a significant increase in measles IgG antibody level is indicative of recent infection. IgM antibodies to measles virus are often detectable with onset of the rash and typically persist for 4 weeks. At least 80% of patients will be positive for measles IgM at 6 days and 100% at 16 days after onset of symptoms.