BAFF ELISA Kit

Catalog No. ABIN2042355

Product Details BAFF ELISA Kit

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 46.9-3000 pg/mL

Minimum Detection Limit: 46.9 pg/mL

Application: ELISA

Brand: BioAssay™

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivity: < 10 pg/mL

Components: 96-well plate pre-coated with anti-BAFF, Mouse
Lyophilized recombinant BAFF, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Application Details

Plate: Pre-coated

Protocol: Sandwich ELISA quantitative detection kit for Mouse BAFF in cell culture supernates, serum and plasma (heparin, EDTA).B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFLSF13B gene.1,2 BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.3All these ligands act as heterotrimers (i.e. three of the same molecule) interacting with heterotrimeric receptors4, although BAFF has been known to be active as either a hetero- or homotrimer.5 The standard used in this kit is recombinant mouse soluble BAFF (A127-L309) with molecular weight 23.2kD.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: BAFF (TNFSF13B Products)

Synonyms: BAFF ELISA Kit, BLYS ELISA Kit, CD257 ELISA Kit, DTL ELISA Kit, TALL-1 ELISA Kit, TALL1 ELISA Kit, THANK ELISA Kit, TNFSF20 ELISA Kit, ZTNF4 ELISA Kit, BAFF-R ELISA Kit, BAFFR ELISA Kit, BROMIX ELISA Kit, CD268 ELISA Kit, CVID4 ELISA Kit, prolixin ELISA Kit, TNFSF13B ELISA Kit, RGD1561519 ELISA Kit, RGD1560810 ELISA Kit, BLyS ELISA Kit, D8Ertd387e ELISA Kit, zTNF4 ELISA Kit, 2010006P15Rik ELISA Kit, Baffr ELISA Kit, Bcmd ELISA Kit, Bcmd-1 ELISA Kit, Bcmd1 ELISA Kit, Lvis22 ELISA Kit, zgc:172115 ELISA Kit, TNF superfamily member 13b ELISA Kit, TNF receptor superfamily member 13C ELISA Kit, tumor necrosis factor (ligand) superfamily, member 13b ELISA Kit, tumor necrosis factor receptor superfamily, member 13c ELISA Kit, tumor necrosis factor superfamily member 13b ELISA Kit, TNFSF13B ELISA Kit, TNFRSF13C ELISA Kit, Tnfsf13b ELISA Kit, Tnfrsf13c ELISA Kit, tnfsf13b ELISA Kit

Gene ID: 24099

UniProt: Q3KP92

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response