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ErbB2/Her2 ELISA Kit

ErbB2/Her2 Reactivity: Human Colorimetric Competition ELISA 15.6-1000 pg/mL
Catalog No. ABIN2042457
  • Target See all ErbB2/Her2 ELISA Kits
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Reactivity
    • 13
    • 8
    • 7
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Competition ELISA
    Detection Range
    15.6-1000 pg/mL
    Minimum Detection Limit
    15.6 pg/mL
    Application
    ELISA
    Brand
    BioAssay™
    Analytical Method
    Quantitative
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Sensitivity
    < 10 pg/mL
    Components
    96-well plate pre-coated with anti-ErbB-2, Human
    Lyophilized recombinant ErbB-2, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • Plate
    Pre-coated
    Protocol
    Sandwich ELISA quantitative detection kit for Human ErbB-2 in cell culture supernates, serum, plasma (heparin, EDTA) and tissue homogenates.HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340 (cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.1 The HER2 gene is a proto-oncogene located at the long arm of human chromosome 17(17q21-q22)2.
    Restrictions
    For Research Use only
  • Storage
    4 °C/-20 °C
  • Target See all ErbB2/Her2 ELISA Kits
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Alternative Name
    ErbB-2 (ErbB2/Her2 Products)
    Synonyms
    CD340 ELISA Kit, HER-2 ELISA Kit, HER-2/neu ELISA Kit, HER2 ELISA Kit, MLN 19 ELISA Kit, NEU ELISA Kit, NGL ELISA Kit, TKR1 ELISA Kit, Erbb-2 ELISA Kit, Neu ELISA Kit, c-erbB2 ELISA Kit, c-neu ELISA Kit, mKIAA3023 ELISA Kit, wu:fv70f10 ELISA Kit, zgc:63601 ELISA Kit, erb2 ELISA Kit, erb-b2 receptor tyrosine kinase 2 ELISA Kit, ERBB2 ELISA Kit, Erbb2 ELISA Kit, erbb2 ELISA Kit
    Gene ID
    2064
    UniProt
    P04626
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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