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Granulin ELISA Kit

GRN Reactivity: Human Colorimetric Sandwich ELISA 1.6-100 ng/mL
Catalog No. ABIN2042639
  • Target See all Granulin (GRN) ELISA Kits
    Granulin (GRN)
    Reactivity
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    1.6-100 ng/mL
    Minimum Detection Limit
    1.6 ng/mL
    Application
    ELISA
    Brand
    BioAssay™
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Sensitivity
    < 50 pg/mL
    Components
    96-well plate pre-coated with anti-Progranulin, Human
    Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • Plate
    Pre-coated
    Protocol
    Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
    Restrictions
    For Research Use only
  • Storage
    4 °C/-20 °C
  • Target See all Granulin (GRN) ELISA Kits
    Granulin (GRN)
    Alternative Name
    Progranulin (GRN Products)
    Synonyms
    GRN ELISA Kit, grn ELISA Kit, wu:fb11g12 ELISA Kit, wu:fj18f05 ELISA Kit, MGC53354 ELISA Kit, DKFZp459H066 ELISA Kit, CLN11 ELISA Kit, GEP ELISA Kit, GP88 ELISA Kit, PCDGF ELISA Kit, PEPI ELISA Kit, PGRN ELISA Kit, epithelin ELISA Kit, acrogranin ELISA Kit, granulin precursor ELISA Kit, granulin a ELISA Kit, Granulins ELISA Kit, granulin L homeolog ELISA Kit, granulin ELISA Kit, GRN ELISA Kit, grna ELISA Kit, grn ELISA Kit, grn.L ELISA Kit, granulin ELISA Kit, ORF1 granulin ELISA Kit, Grn ELISA Kit
    Target Type
    Viral Protein
    Gene ID
    2896
    UniProt
    P28799
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