ASGPR Ab ELISA Kit
ASGPR Ab
Reactivity: Human
Colorimetric
Plasma, Serum
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- Target See all ASGPR Ab products
- ASGPR Ab (Asialoglyco Protein Receptor Antibody (ASGPR Ab))
- Reactivity
- Human
- Detection Method
- Colorimetric
- Application
- ELISA
- Purpose
- Anti-ASGPR (Asialoglycoprotein Receptor) ELISA Assay Kit is used for the semi-quantitative determination of IgG antibodies to asialoglycoprotein receptor (ASGPR) in human serum or plasma.
- Sample Type
- Serum, Plasma
- Analytical Method
- Semi-Quantitative
- Sensitivity
- Cut Off Control
- Characteristics
- ASGPR is a liver specific membrane receptor playing a pivotal role in the endocytosis of glycoproteins from the blood. An induction of humoral and cellular immune mechanisms to the ASGPR has been observed in the course of inflammatory liver disorders especially autoimmune hepatitis. The level of ASGPR autoantibodies correlates with the severity of the disease and declines under therapy.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Sample Volume
- 100 μL
- Assay Time
- 2 h
- Protocol
- Anti-ASGPR (Asialoglycoprotein Receptor) ELISA Assay is an enzyme immunoassay for the semi-quantitative determination of IgG antibodies to ASGPR. The antibodies of the calibrators and diluted samples react with ASGPR immobilized on the solid phase of microtiter plates. ASGPR highly purified from rabbit liver and coated on the microtiter plate guarantees the specific binding of ASGPR IgG antibodies of the specimen under investigation. Following an incubation period of 60 min at 37 °C, unbound serum components are removed by a washing step.
- Restrictions
- For Research Use only
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- Storage
- 4 °C
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- Target See all ASGPR Ab products
- ASGPR Ab (Asialoglyco Protein Receptor Antibody (ASGPR Ab))
- Alternative Name
- Anti-ASGPR (Asialoglycoprotein Receptor) (ASGPR Ab Products)
- Target Type
- Antibody
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