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FNDC5 ELISA Kit

FNDC5 Reactivity: Human, Mouse, Rat, Monkey Colorimetric Competition ELISA 0.001-5 μg/mL Cell Culture Supernatant, Plasma, Serum
Catalog No. ABIN2745463
  • Target See all FNDC5 ELISA Kits
    FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
    Reactivity
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey
    Detection Method
    Colorimetric
    Method Type
    Competition ELISA
    Detection Range
    0.001-5 μg/mL
    Minimum Detection Limit
    0.001 μg/mL
    Application
    ELISA
    Sample Type
    Cell Culture Supernatant, Plasma, Serum
    Analytical Method
    Quantitative
    Specificity
    Detects human irisin. It should also work in mouse, rat and monkey biological samples.
    Cross-Reactivity
    Human, Monkey, Mouse (Murine), Rat (Rattus)
    No Cross-Reactivity
    Mouse (Murine)
    Cross-Reactivity (Details)
    Does not cross-react with FNDC4, human adiponectin, human Nampt, human RBP4, human clusterin, human leptin, human vaspin, human GPX3, human resistin, human ACE2, human lipocalin-2, human ANGPTL3, human ANGPTL6, human DNER, human DLK1, human calreticulin, human IL-33, mouse Nampt, mouse clusterin, mouse vaspin or mouse resistin.
    Sensitivity
    1 ng/mL
    Characteristics
    Irisin Competitive ELISA Kit
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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: +4°C
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • Target See all FNDC5 ELISA Kits
    FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
    Alternative Name
    Irisin (FNDC5 Products)
    Synonyms
    FRCP2 ELISA Kit, irisin ELISA Kit, 1500001L03Rik ELISA Kit, AI836596 ELISA Kit, C87088 ELISA Kit, PeP ELISA Kit, Pxp ELISA Kit, fndc5 ELISA Kit, si:dkey-264p5.1 ELISA Kit, zgc:158684 ELISA Kit, fibronectin type III domain containing 5 ELISA Kit, fibronectin type III domain containing 5b ELISA Kit, FNDC5 ELISA Kit, Fndc5 ELISA Kit, fndc5b ELISA Kit
    Background
    Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Circulating irisin levels were shown to be upregulated after acute exercise. Increase of irisin under conditions of obesity may indicate a physiological function to improve glucose tolerance.
    UniProt
    Q8NAU1
    Pathways
    Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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