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Helicobacter Pylori IgA (Hp-IgA) ELISA Kit

Reactivity: Human Colorimetric Competition ELISA Serum
Catalog No. ABIN997007
  • Target
    Helicobacter Pylori IgA (Hp-IgA)
    Reactivity
    • 2
    • 1
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    Human
    Detection Method
    Colorimetric
    Method Type
    Competition ELISA
    Application
    ELISA
    Purpose
    Helicobacter pylori IgA is intended for use in evaluating the serologic status to H. pylori infection in patients with gastrointestinal symptoms.
    Sample Type
    Serum
    Analytical Method
    Qualitative
    Specificity
    97.10%
    Sensitivity
    88.90%
  • Sample Volume
    5 μL
    Assay Time
    1 - 2 h
    Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C
    Expiry Date
    12-18 months
  • Target
    Helicobacter Pylori IgA (Hp-IgA)
    Target Type
    Antibody
    Background
    Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa by Marshall in 1982. Studies have indicated that the presence of H. pylori is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. The studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. Patients who present with clinical symptoms relating to the gastrointestinal tract can be diagnosed for H. pylori infection by two methods: 1) invasive techniques include biopsy followed by culture or histologic examination of biopsy specimen or direct detection of urease activity. 2) non-invasive techniques include urea breath tests, serological methods and stool antigen test. All of the testing performed on biopsy samples are subject to errors related to sampling and interference of contaminated bacteria. H. pylori IgA, testing the presence of H. pylori specific IgA antibody is the technique of choice for serologic tests because of its accuracy and simplicity.
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