HTLV ELISA Kit
Reactivity: Human T-lymphotropic Virus (HTLV)
Colorimetric
Sandwich ELISA
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- Target
- HTLV
- Reactivity
- Human T-lymphotropic Virus (HTLV)
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Application
- ELISA
- Purpose
- anti-HTLV 1+2 ELISA is an enzyme-linked immunosorbent assay (ELISA) for qualitative detection of antibodies to Human T-Cell Lymphotropic Virus types 1 and/or 2 (HTLV-1/2) in human serum or plasma
- Analytical Method
- Qualitative
- Specificity
- 99.90%
- Sensitivity
- 100%
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- Sample Volume
- 50 μL
- Assay Time
- 1 - 2 h
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C
- Expiry Date
- 12-18 months
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- Target
- HTLV
- Target Type
- Virus
- Background
- The human T-cell lymphotropic viruses (HTLV) is a member of the family of Retroviridae, consisting of enveloped double stranded RNA viruses and genetically not related to HIV1&2, however, they have similar routes of transmission and can have extremely long period of latency prior to manifestation of disease. HTLV type 1 was reported in 1980 as the first retrovirus shown to be pathogenic to humans. The virus preferentially infects CD4+ lymphocytes while the infections of CD8+ T lymphocytes are rare. In contrast to HTLV 1, HTLV type 2 can infect all type of lymphocytes as well as the macrophages. HTLV 1&2 is transmitted transplacentally, parenterally, by sexual contacts and by infected blood. The diseases associated with HTLV infection are usually classified as malignant or nonmalignant clinical presentations. HTLV 1 is endemic in southern Japan, the Caribbean and the US and many other scattered population through the world. HTLV 2 is endemic in some North American Indian tribes but is detected mostly in intravenous drug users and their sexual partners.
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