We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Dynein, Light Chain, LC8-Type 1 (DYNLL1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus), Fruit Fly (Drosophila melanogaster) Alternatives|
Western Blotting (WB)
|Supplier||Log in to see|
Product detailsTarget Details Application Details Handling Images
|Specificity||DYNLL1 antibody was raised against the N terminal of DYNLL1|
|Immunogen||DYNLL1 antibody was raised using the N terminal of DYNLL1 corresponding to a region with amino acids MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKY|
Target DetailsProduct details Application Details Handling Images back to top
|Alternative Name||DYNLL1 (DYNLL1 Antibody Abstract)|
|Background||Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kDa. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.|
|Molecular Weight||10 kDa (MW of target protein)|
|Pathways||M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity|
Application DetailsProduct details Target Details Handling Images back to top
WB: 1 µg/mL
Optimal conditions should be determined by the investigator.
DYNLL1 Blocking Peptide, catalog no. 33R-5809, is also available for use as a blocking control in assays to test for specificity of this DYNLL1 antibody
|Restrictions||For Research Use only|
HandlingProduct details Target Details Application Details Images back to top
|Reconstitution||Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DYNLL1 antibody in PBS|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.|