anti-Human Dynein, Light Chain, LC8-Type 1 antibody for Western Blotting

Recommended Dynein, Light Chain, LC8-Type 1 Antibody (supplied by: Log in to see )

Antigen
Dynein, Light Chain, LC8-Type 1 (DYNLL1) Antibodies
  • lc8
  • dlc1
  • dlc8
  • lc8a
  • dncl1
  • dnclc1
  • dynll1a
  • MGC68763
  • pin
  • hdlc1
  • MGC89636
  • LC8
  • rhogap7
  • ARHGAP7
  • Dlc-1
  • STARD12
  • DLC-1
  • StARD12
  • A730069N07Rik
  • Arhgap7
  • HP
  • dlc-1
  • RhoGAP
  • DLC1
  • F56
  • Dlc8
  • Dnclc1
  • Pin
  • 8kDLC
  • DLC8
  • DNCL1
  • DNCLC1
  • LC8a
  • PIN
  • dynll1
  • dynll1b
  • DYNLL1
  • CDLC2
  • dynll2
  • wu:fd56c09
  • zgc:73406
  • dynein, light chain, LC8-type 1
  • deleted in liver cancer 1
  • deleted in lung and esophageal cancer 1
  • dynein light chain LC8-type 1
  • Protein DLC-1
  • dynll1-a
  • dynll1
  • DYNLL1
  • dlc1
  • DLC1
  • Dlc1
  • DLEC1
  • Dynll1
  • dynll1-b
  • LOC770215
  • dlc-1
Epitope
N-Term
6
5
3
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
60
20
19
6
6
6
6
6
5
4
4
4
4
4
3
3
3
1
Host
Rabbit
34
24
3
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
3
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
55
17
14
8
5
5
5
2
2
1
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Catalog No. ABIN2784529
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1438015 ABIN2784485 WB Rabbit Middle Region Log in to see Polyclonal 1
3.1438015 ABIN2784486 WB Rabbit Middle Region Log in to see Polyclonal
3.1438015 ABIN968140 IHC (f) IF IP WB Mouse IgG1 AA 1-89 Log in to see 4-PIN 2
3.1438015 ABIN2459478 ELISA WB Rabbit Log in to see Polyclonal
3.1438015 ABIN4890429 WB Rabbit N-Term Log in to see Polyclonal
3.1438015 ABIN522102 IF ELISA WB Mouse IgG2a kappa AA 1-72, partial Log in to see 1H7
3.1438015 ABIN4890444 WB Rabbit Log in to see Polyclonal
3.1438015 ABIN2562321 IHC WB Rabbit IgG Log in to see Polyclonal
3.1438015 ABIN5078832 ICC IF WB Rabbit IgG Log in to see Polyclonal
3.1438015 ABIN2423315 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN768961 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN768963 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN321948 WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN799132 WB Rabbit AA 33-82 Log in to see Polyclonal
1 ABIN199115 FACS WB Rat IgM Log in to see
1 ABIN200808 FACS IP WB Rat IgG2a Log in to see
1 ABIN1955746 ELISA IHC IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN1958087 ELISA IHC IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN1956980 ELISA IHC IHC (p) WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN4238213 WB Rabbit Log in to see Polyclonal

General

Antigen Dynein, Light Chain, LC8-Type 1 (DYNLL1) Antibodies
Epitope N-Term
(6), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
(60), (20), (19), (6), (6), (6), (6), (6), (5), (4), (4), (4), (4), (4), (3), (3), (3), (1)
Host Rabbit
(34), (24), (3)
Clonality
Polyclonal
Conjugate Un-conjugated
(4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(55), (17), (14), (8), (5), (5), (5), (2), (2), (1)
Pubmed 1 reference available
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Product details

Target details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN976056
Sequence MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against DYNLL1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DYNLL1

Target details

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Antigen
Alternative Name DYNLL1 (DYNLL1 Antibody Abstract)
Background Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Alias Symbols: DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, MGC126137, MGC126138, PIN, hdlc1
Protein Interaction Partner: UBC, DYNC1I1, CCDC36, IQUB, AMBRA1, AMOTL2, KANK2, BECN1, BMI1, EED, GNB2L1, RPS21, RPS5, RPS3, RPS2, RPSA, HDLBP, FKBP3, FAU, DYNC1LI2, NRF1, AMOT, DYRK1B, DYRK1A, TERT, STK24, PRKACB, PRKACA, GSK3B, STK26, STK25, CSNK1A1, PAK1, UL122, IQCB1, BCL2L11, NA
Protein Size: 89
Molecular Weight 10 kDa
Gene ID 8655
NCBI Accession NM_001037494, NP_001032583
UniProt P63167
Pathways M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 89 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Song, Wen, Rayala, Chen, Ma, Zhang, Kumar: "Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions." in: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4004-13, 2008

Images

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Supplier Images
Western Blotting (WB) image for anti-Dynein, Light Chain, LC8-Type 1 (DYNLL1) (N-Term) antibody (ABIN2784529) WB Suggested Anti-DYNLL1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positiv...