anti-Human MXI1 antibody for Enzyme Immunoassay

Recommended MXI1 Antibody

Antigen
MAX Interactor 1 (MXI1) Antibodies
  • mxi
  • mad2
  • mxd2
  • xmxi1
  • MGC89544
  • MXI1
  • etID309773.22
  • fb16b12
  • fb55f03
  • wu:fb16b12
  • wu:fb55f03
  • wu:fd06a08
  • wu:fz74f10
  • ENSMUSG00000067085
  • Gm10197
  • Mad2
  • bHLHc11
  • MXI-WR
  • MAD2
  • MXD2
  • MXI
  • MAX interactor 1, dimerization protein
  • max interactor 1, dimerization protein
  • MAX interactor 1, dimerization protein L homeolog
  • mxi1
  • MXI1
  • Mxi1
  • mxi1.L
Epitope
AA 52-82, Middle Region
9
7
7
7
4
3
3
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
51
42
23
6
5
5
4
4
3
2
2
2
2
2
1
Host
Rabbit
52
10
3
Clonality
Polyclonal
Conjugate
This MXI1 antibody is un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
50
28
7
5
3
3
2
1
1
Options

Available images

Catalog No. ABIN953554
$ 484.00
Plus shipping costs $45.00

General

Antigen MAX Interactor 1 (MXI1) Antibodies
Epitope AA 52-82, Middle Region
(9), (7), (7), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(51), (42), (23), (6), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1)
Host Rabbit
(52), (10), (3)
Clonality
Polyclonal
Conjugate This MXI1 antibody is un-conjugated
(4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(50), (28), (7), (5), (3), (3), (2), (1), (1)
Pubmed 3 references available
Supplier

Product Details anti-MXI1 Antibody

Target Details MXI1 Application Details Handling References for anti-MXI1 antibody (ABIN953554) Images
Specificity This antibody recognizes human and mouse MXI1.
Purification Purified through a Protein A column followed by peptide affinity purification
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 52-82aa) of human MXI1.
Isotype Ig Fraction
Plasmids, Primers & others

Target Details MXI1

Product Details anti-MXI1 Antibody Application Details Handling References for anti-MXI1 antibody (ABIN953554) Images back to top
Antigen
Alternative Name MXI1 (MXI1 Antibody Abstract)
Background Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.Synonyms: Class C basic helix-loop-helix protein 11, MAX-interacting protein 1, Max interactor 1, bHLHc11
Molecular Weight 26062 Da
Gene ID 4601
NCBI Accession NP_005953
Pathways Maintenance of Protein Location

Application Details

Product Details anti-MXI1 Antibody Target Details MXI1 Handling References for anti-MXI1 antibody (ABIN953554) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details References for anti-MXI1 antibody (ABIN953554) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-MXI1 antibody (ABIN953554)

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Handling Images back to top
Background publications

Löfstedt, Fredlund, Noguera, Navarro, Holmquist-Mengelbier, Beckman, Påhlman, Axelson: "HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells." in: Experimental cell research, Vol. 315, Issue 11, pp. 1924-36, 2009

Baranzini, Wang, Gibson, Galwey, Naegelin, Barkhof, Radue, Lindberg, Uitdehaag, Johnson, Angelakopoulou, Hall, Richardson, Prinjha, Gass, Geurts, Kragt, Sombekke, Vrenken, Qualley, Lincoln et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." in: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, 2009

Tsao, Teh, Jonasch, Shreiber-Agus, Efstathiou, Hoang, Czerniak, Logothetis, Corn: "Inhibition of Mxi1 suppresses HIF-2alpha-dependent renal cancer tumorigenesis." in: Cancer biology & therapy, Vol. 7, Issue 10, pp. 1619-27, 2008

Images

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Handling References for anti-MXI1 antibody (ABIN953554) back to top
Supplier Images
Western Blotting (WB) image for anti-MAX Interactor 1 (MXI1) (AA 52-82), (Middle Region) antibody (ABIN953554) Western blot analysis in mouse heart tissue lysates (35ug/lane) using MXI1 Antibody ....