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|Antigen||Calnexin (CANX) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Chicken, Bird (Avian), Donkey, Cat (Feline), Goat, Guinea Pig, Hamster, Horse (Equine), Pig (Porcine), Rabbit, Sheep (Ovine), Monkey, Others Alternatives|
|Conjugate||This Calnexin antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Western Blotting (WB)
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Product Details anti-Calnexin AntibodyTarget Details Calnexin Application Details Handling Images
|Specificity||Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118, rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates.|
|Purification||This antibody is epitope-affinity purified from goat antiserum|
|Immunogen||Purified recombinant peptide within residues 550 AA to the C-terminus of human CANX produced in E. coli.|
Target Details CalnexinProduct Details anti-Calnexin Antibody Application Details Handling Images back to top
|Alternative Name||CANX (CANX Antibody Abstract)|
CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Synonyms: Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.
Ensembl identifier: ENSG00000127022
|Pathways||MAPK Signaling, Thyroid Hormone Synthesis|
Application DetailsProduct Details anti-Calnexin Antibody Target Details Calnexin Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-Calnexin Antibody Target Details Calnexin Application Details Images back to top
|Buffer||Polyclonal antibody supplied as a 200 µL (2 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide|
|Handling Advice||The antibody solution should be gently mixed before use.|
|Storage||4 °C/-20 °C|
|Storage Comment||For continuous use, store at 2-8 °C for one-two days. For extended storage, store in -20 °C freezer. Working dilution samples should be discarded if not used within 12 hours.|
ImagesProduct Details anti-Calnexin Antibody Target Details Calnexin Application Details Handling back to top