anti-Human ELK1 antibody for Enzyme Immunoassay

Recommended ELK1 Antibody (supplied by: Log in to see )

Antigen
ELK1, Member of ETS Oncogene Family (ELK1) Antibodies
  • Elk-1
  • Xelk
  • Xelk-1
  • elk-1
  • elk1
  • ELK1, ETS transcription factor
  • ELK1, member of ETS oncogene family
  • ETS domain-containing protein Elk-1
  • ELK1, member of ETS oncogene family S homeolog
  • ELK1
  • Elk1
  • Tsp_02690
  • elk1
  • elk1.S
Reactivity
Human
344
209
195
22
18
13
13
12
7
6
5
3
3
2
2
1
Host
Mouse
303
41
Clonality
Monoclonal
Conjugate
This ELK1 antibody is un-conjugated
6
6
6
4
4
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
233
157
118
58
47
40
38
9
6
6
3
2
1
1
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Catalog No. ABIN1107085
$ 489.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN318012 EIA IHC (p) IP WB Rabbit pSer383 Log in to see Polyclonal 0
4 ABIN358791 EIA WB Rabbit Ig Fraction Ser383 Log in to see Polyclonal 5
4 ABIN1107086 EIA WB Mouse IgG1 Log in to see 7E10D5 4
1 ABIN452640 EIA Mouse IgG1 pSer383 Log in to see B4A12 0
1 ABIN452642 EIA Mouse IgG2b pSer383 Log in to see D7H2 0
1 ABIN2720129 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen ELK1, Member of ETS Oncogene Family (ELK1) Antibodies
Reactivity Human
(344), (209), (195), (22), (18), (13), (13), (12), (7), (6), (5), (3), (3), (2), (2), (1)
Host Mouse
(303), (41)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ELK1 antibody is un-conjugated
(6), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(233), (157), (118), (58), (47), (40), (38), (9), (6), (6), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-ELK1 Antibody

Target Details ELK1 Application Details Handling References for anti-ELK1 antibody (ABIN1107085) Images
Specificity Recognizes ELK1
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Clone 3H6D12
Isotype IgG1
Plasmids, Primers & others

Target Details ELK1

Product Details anti-ELK1 Antibody Application Details Handling References for anti-ELK1 antibody (ABIN1107085) Images back to top
Antigen
Alternative Name ELK1 (ELK1 Antibody Abstract)
Background The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.Synonyms: ETS domain-containing protein Elk-1, Elk-1
Gene ID 2002
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-ELK1 Antibody Target Details ELK1 Handling References for anti-ELK1 antibody (ABIN1107085) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details References for anti-ELK1 antibody (ABIN1107085) Images back to top
Format Liquid
Buffer 0.03 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-ELK1 antibody (ABIN1107085)

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details Handling Images back to top
Background publications

Hsieh, Wu, Tsai, Huang, Hsieh, Liu: "PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells." in: Biochemical and biophysical research communications, Vol. 339, Issue 1, pp. 217-25, 2005

Gille, Strahl, Shaw: "Activation of ternary complex factor Elk-1 by stress-activated protein kinases." in: Current biology : CB, Vol. 5, Issue 10, pp. 1191-200, 1996

Gille, Kortenjann, Thomae, Moomaw, Slaughter, Cobb, Shaw: "ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation." in: The EMBO journal, Vol. 14, Issue 5, pp. 951-62, 1995

Rao, Huebner, Isobe, ar-Rushdi, Croce, Reddy: "elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints." in: Science (New York, N.Y.), Vol. 244, Issue 4900, pp. 66-70, 1989

Images

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details Handling References for anti-ELK1 antibody (ABIN1107085) back to top
Supplier Images
Western Blotting (WB) image for anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody (ABIN1107085) anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody
Immunohistochemistry (IHC) image for anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody (ABIN1107085) anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody (Image 2)