anti-Human ELK1 antibody for ELISA

Recommended ELK1 Antibody (supplied by: Log in to see )

Antigen
ELK1, Member of ETS Oncogene Family (ELK1) Antibodies
  • Elk-1
  • Xelk
  • Xelk-1
  • elk-1
  • elk1
  • ELK1, ETS transcription factor
  • ELK1, member of ETS oncogene family
  • ETS domain-containing protein Elk-1
  • ELK1, member of ETS oncogene family S homeolog
  • ELK1
  • Elk1
  • Tsp_02690
  • elk1
  • elk1.S
Reactivity
Human
341
210
197
22
18
14
13
12
7
6
5
3
3
2
1
1
Host
Mouse
302
40
Clonality
Monoclonal
Conjugate
This ELK1 antibody is un-conjugated
6
6
6
4
4
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
230
156
115
58
48
40
38
9
7
6
3
2
1
1
Options
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Catalog No. ABIN969095
$ 490.60
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
20.255764 ABIN969096 ELISA WB Mouse IgG1 Log in to see 7E10D5 4
18.755764 ABIN931350 IHC ELISA WB Mouse IgG1 Log in to see 3H6D12-4H9C8?4H9F1 0
17.255764 ABIN966064 IHC ELISA WB IgG1 Log in to see 4
17.255764 ABIN966065 ELISA WB IgG1 Log in to see 4
15.755764 ABIN3184458 ELISA IHC IP WB Rabbit IgG Ser334 Log in to see Polyclonal 0
15.755764 ABIN3184456 ELISA IF IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0
15.755764 ABIN3184457 ELISA IHC IP WB Rabbit IgG Ser334 Log in to see Polyclonal 0
15.755764 ABIN931351 ELISA WB Mouse IgG1 Log in to see 7E10D5?7E10E8 0
13 ABIN6256307 ELISA ICC IF IHC IP WB Rabbit IgG pSer383 Log in to see Polyclonal 0
13 ABIN6256309 ELISA ICC IF IHC IP WB Rabbit IgG pSer389 Log in to see Polyclonal 0
12.755764 ABIN3181994 ELISA IHC IP WB Rabbit IgG pSer383 Log in to see Polyclonal 0
12.755764 ABIN3181995 ELISA IHC IP WB Rabbit IgG pSer389 Log in to see Polyclonal 0
12.755764 ABIN3181996 ELISA IHC IP Rabbit IgG pThr417 Log in to see Polyclonal 0
12.755764 ABIN3184459 ELISA IHC Rabbit IgG Ser336 Log in to see Polyclonal 0
12.755764 ABIN4901442 ELISA WB Mouse IgG1 Log in to see 7E10D5-7E10E8 0
12.755764 ABIN4901441 ELISA IHC (p) WB Mouse IgG1 Log in to see 3H6D12-4H9C8-4H9F1 0
12.755764 ABIN2139839 ELISA WB Rabbit IgG Log in to see Polyclonal 0
12.755764 ABIN2139840 ELISA WB Rabbit IgG Log in to see Polyclonal 0
12.755764 ABIN2139841 IHC ELISA WB Rabbit IgG pSer383 Log in to see Polyclonal 0
12.755764 ABIN2139842 IF IHC ELISA WB Rabbit IgG Ser383 Log in to see Polyclonal 0

General

Antigen ELK1, Member of ETS Oncogene Family (ELK1) Antibodies
Reactivity Human
(341), (210), (197), (22), (18), (14), (13), (12), (7), (6), (5), (3), (3), (2), (1), (1)
Host Mouse
(302), (40)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ELK1 antibody is un-conjugated
(6), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(230), (156), (115), (58), (48), (40), (38), (9), (7), (6), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-ELK1 Antibody

Target Details ELK1 Application Details Handling References for anti-ELK1 antibody (ABIN969095) Images
Purification Ascites
Immunogen Purified recombinant fragment of ELK1 expressed in E. Coli.
Clone 3H6D12
Isotype IgG1
Plasmids, Primers & others

Target Details ELK1

Product Details anti-ELK1 Antibody Application Details Handling References for anti-ELK1 antibody (ABIN969095) Images back to top
Antigen
Alternative Name ELK1 (ELK1 Antibody Abstract)
Background The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.
Gene ID 2002
HGNC 2002
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-ELK1 Antibody Target Details ELK1 Handling References for anti-ELK1 antibody (ABIN969095) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details References for anti-ELK1 antibody (ABIN969095) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-ELK1 antibody (ABIN969095)

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details Handling Images back to top
Product cited in:

Hsieh, Wu, Tsai, Huang, Hsieh, Liu: "PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells." in: Biochemical and biophysical research communications, Vol. 339, Issue 1, pp. 217-25, 2005

Background publications

Gille, Strahl, Shaw: "Activation of ternary complex factor Elk-1 by stress-activated protein kinases." in: Current biology : CB, Vol. 5, Issue 10, pp. 1191-200, 1996

Gille, Kortenjann, Thomae, Moomaw, Slaughter, Cobb, Shaw: "ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation." in: The EMBO journal, Vol. 14, Issue 5, pp. 951-62, 1995

Rao, Huebner, Isobe, ar-Rushdi, Croce, Reddy: "elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints." in: Science (New York, N.Y.), Vol. 244, Issue 4900, pp. 66-70, 1989

Images

Product Details anti-ELK1 Antibody Target Details ELK1 Application Details Handling References for anti-ELK1 antibody (ABIN969095) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody (ABIN969095) Figure 1: Immunohistochemical analysis of paraffin-embedded human brain tumor tissue,...
Western Blotting (WB) image for anti-ELK1, Member of ETS Oncogene Family (ELK1) antibody (ABIN969095) Figure 2: Western blot analysis using ELK1 mouse mAb against truncated ELK1 recombina...