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|Antigen||Mitogen-Activated Protein Kinase 1 (MAPK1) Antibodies|
|Epitope||AA 1-360, N-Term Alternatives|
|Conjugate||This ERK2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-ERK2 AntibodyTarget Details ERK2 Application Details Handling Images
|Specificity||The antibody recognizes human MAPK1. Other species not tested.|
|Characteristics||Synonyms: Mitogen-activated protein kinase 1, p42-MAPK, ERT1, PRKM1, PRKM2, MAP kinase 2,MAPK2, MAPK1, Extracellular signal-regulated kinase 2|
|Purification||Protein-G affinity chromatography|
|Immunogen||Recombinant human MAPK1 (1-360aa) purified from E. coli|
|Plasmids, Primers & others|
Target Details ERK2Product Details anti-ERK2 Antibody Application Details Handling Images back to top
|Alternative Name||ERK2 (MAPK1 Antibody Abstract)|
|Background||Mitogen-activated protein kinases (MAPKs) are reported to be critical regulatory factors for the growth andmigration of various cell types including vascular smooth muscle cells (VSMCs). It has also been reported that the activation of the MAP kinase family, extracellular signal regulated kinases 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) via Src activation is important for AII-induced migration of VSMCs. MAPKs are intracellular signal-transduction pathways that have been shown to play a central role in the development of injury following ischemia in the brain and heart. MAPKs regulate gene expression, which is important in cell injury/repair and proliferation/differentiation.Synonyms: ERT1, Extracellular signal-regulated kinase 2, MAP kinase 2, MAPK1, MAPK2, Mitogen-activated protein kinase 1, PRKM1, PRKM2, p42-MAPK|
|Pathways||MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals|
Application DetailsProduct Details anti-ERK2 Antibody Target Details ERK2 Handling Images back to top
ELISA. Western blot (1: 500 - 1: 3,000). Immunofluorescence (1: 500 - 1: 3,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-ERK2 Antibody Target Details ERK2 Application Details Images back to top
|Buffer||PBS, pH 7.4, containing 0.09 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
ImagesProduct Details anti-ERK2 Antibody Target Details ERK2 Application Details Handling back to top