anti-Mouse (Murine) HSPB1 antibody for Immunofluorescence (Paraffin-embedded Sections)
Recommended HSPB1 Antibody (supplied by: Log in to see )
- Antigen
-
Heat Shock 27kDa Protein 1 (HSPB1) Antibodies
show synonyms for this antigen- CMT2F
- HMN2B
- HS.76067
- HSP27
- HSP28
- Hsp25
- SRP27
- 27kDa
- Hsp27
- cb153
- cb660
- hsp1
- hsp25
- hsp27
- id:ibd2821
- sb:cb660
- zgc:103437
- HSPB1
- cmt2f
- hs.76067
- hsp28
- heat shock protein family B (small) member 1
- heat shock protein 1
- heat shock protein, alpha-crystallin-related, 1
- heat shock protein family B (small) member 1 L homeolog
- HSPB1
- Hspb1
- hspb1
- hspb1.L
- Epitope
-
AA 100-150
Alternatives - Reactivity
-
Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This HSPB1 antibody is un-conjugated
Alternatives - Application
-
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN901433 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN901429 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN901431 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN901432 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN672445 | IF (p) | Cy5 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN672444 | IF (p) | Cy3 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN672446 | IF (p) | Cy5.5 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN672447 | IF (p) | Cy7 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN672448 | IF (p) | FITC | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN2814545 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | AA 100-150 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN877141 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN685322 | IF (p) | Cy5 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN685324 | IF (p) | Cy7 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN685325 | IF (p) | FITC | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN685321 | IF (p) | Cy3 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN685323 | IF (p) | Cy5.5 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN877138 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN877142 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN877140 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN2814547 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | pSer82 | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Heat Shock 27kDa Protein 1 (HSPB1) Antibodies |
| Epitope | AA 100-150 Alternatives |
| Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This HSPB1 antibody is un-conjugated Alternatives |
| Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
|
|
2 references available |
| Supplier | Log in to see |
Product Details anti-HSPB1 AntibodyTarget Details HSPB1 Application Details Handling References for anti-HSPB1 antibody (ABIN672441) Images |
|
| Purification | Purified by Protein A. |
| Immunogen | KLH conjugated synthetic peptide derived from human HSP27 |
| Isotype | IgG |
Target Details HSPB1Product Details anti-HSPB1 Antibody Application Details Handling References for anti-HSPB1 antibody (ABIN672441) Images back to top |
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| Antigen | |
| Alternative Name | HSP27 (HSPB1 Antibody Abstract) |
| Background |
Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilize DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex. Subcellular location: Cytoplasm, Nucleus Synonyms: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.7667, HEL-S-12, Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27 |
| Gene ID | 3315 |
| UniProt | P04792 |
| Pathways | MAPK Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling |
Application DetailsProduct Details anti-HSPB1 Antibody Target Details HSPB1 Handling References for anti-HSPB1 antibody (ABIN672441) Images back to top |
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| Application Notes |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-HSPB1 Antibody Target Details HSPB1 Application Details References for anti-HSPB1 antibody (ABIN672441) Images back to top |
|
| Format | Liquid |
| Concentration | 1 μg/μL |
| Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Store at -20°C |
| Expiry Date | 12 months |
References for anti-HSPB1 antibody (ABIN672441)Product Details anti-HSPB1 Antibody Target Details HSPB1 Application Details Handling Images back to top |
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| Product cited in: |
Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human). Further details: Sample: Colon Wang, Yang, Liu, Zhou, Wu, Qiao, Li, Wang: "Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets." in: The Journal of nutrition, Vol. 142, Issue 1, pp. 7-13, 2011 |
ImagesProduct Details anti-HSPB1 Antibody Target Details HSPB1 Application Details Handling References for anti-HSPB1 antibody (ABIN672441) back to top |
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| Supplier Images |
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-HSP27/HspB1/H...
Formalin-fixed and paraffin embedded rat brain labeled with (ABIN672441) Rabbit Ant...
L1 mouse brain lysates L2 mouse liver lysates probed with Anti HSP27/HspB1/HSP25 Poly...
Formalin-fixed and paraffin-embedded rat brain labeled with Anti-HSP27/HspB1/HSP25 Po...
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-HSP27/HspB1/H...
A431 cells probed with HSP27 Polyclonal Antibody, unconjugated at 1:100 dilution for...
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