anti-Human MAP2K2 antibody for Immunofluorescence

Recommended MAP2K2 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Antibodies
  • Prkmk2
  • CFC4
  • MAPKK2
  • MEK2
  • MKK2
  • PRKMK2
  • AA589381
  • MK2
  • ATMKK2
  • F27B13.50
  • F27B13_50
  • MAP KINASE KINASE 1
  • MAP kinase kinase 2
  • MK1
  • mitogen activated protein kinase kinase 2
  • mitogen-activated protein kinase kinase 2
  • MAP kinase kinase 2
  • Map2k2
  • MAP2K2
  • MKK2
Epitope
AA 1-30, N-Term
56
40
25
20
17
16
14
12
10
10
10
7
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
363
181
144
13
12
4
3
2
1
1
Host
Rabbit
252
102
13
1
Clonality
Polyclonal
Conjugate
This MAP2K2 antibody is un-conjugated
19
18
15
7
7
7
5
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Western Blotting (WB)
321
123
121
56
47
43
27
19
15
14
13
11
4
1
Options
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Catalog No. ABIN1882178
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.342966 ABIN2855313 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
11.342966 ABIN519254 IF IP WB Rabbit AA 1-400, full length Log in to see Polyclonal 0
11.342966 ABIN1870344 IF IHC WB Rabbit IgG pThr394 Log in to see Polyclonal 0
11.342966 ABIN519255 IF WB Rabbit AA 1-400, full length Log in to see Polyclonal 0
11.342966 ABIN948323 IF ELISA WB Mouse IgG2b kappa AA 1-360, partial Log in to see 8D10 0
11.342966 ABIN4333500 ELISA FACS ICC IF WB Mouse IgG1 Log in to see 7F5 0
11.342966 ABIN4333503 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
11.342966 ABIN4333502 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
11.342966 ABIN4333504 IF IHC WB Mouse IgG2a Log in to see 1A-2 0
11.342966 ABIN5582996 ELISA FACS IF WB Mouse IgG1 Log in to see 7F5 0
11.342966 ABIN1108139 EIA IF WB Mouse IgG1 Log in to see 7F5 1
11.342966 ABIN4333501 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
11.342966 ABIN2424775 IF IHC WB Rabbit IgG pThr394 Log in to see Polyclonal 0
11.342966 ABIN3019566 IF IHC WB Rabbit pThr394 Log in to see Polyclonal 0
1 ABIN392485 IF IHC (p) WB Rabbit Ig Fraction AA 262-292, Center Log in to see Polyclonal 0
1 ABIN5950421 FACS ICC IF IHC IHC (p) IP WB Rabbit IgG AA 1-100 Log in to see SD207-08 0
1 ABIN5950422 ICC IF IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see SR13-07 0
1 ABIN214275 IF IHC IHC (p) WB Rabbit IgG pThr394 Log in to see Polyclonal 0
1 ABIN1499478 IF WB Mouse IgG1 Log in to see 5B4 0
1 ABIN196622 IF IHC (p) WB Rabbit pThr394 Log in to see Polyclonal 2

General

Antigen Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Antibodies
Epitope AA 1-30, N-Term
(56), (40), (25), (20), (17), (16), (14), (12), (10), (10), (10), (7), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(363), (181), (144), (13), (12), (4), (3), (2), (1), (1)
Host Rabbit
(252), (102), (13), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MAP2K2 antibody is un-conjugated
(19), (18), (15), (7), (7), (7), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Western Blotting (WB)
(321), (123), (121), (56), (47), (43), (27), (19), (15), (14), (13), (11), (4), (1)
Pubmed 5 references available
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Product Details anti-MAP2K2 Antibody

Target Details MAP2K2 Application Details Handling References for anti-MAP2K2 antibody (ABIN1882178) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This MEK2 (MAP2K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MEK2 (MAP2K2).
Clone RB3595
Plasmids, Primers & others

Target Details MAP2K2

Product Details anti-MAP2K2 Antibody Application Details Handling References for anti-MAP2K2 antibody (ABIN1882178) Images back to top
Antigen
Alternative Name MEK2 (MAP2K2) (MAP2K2 Antibody Abstract)
Background MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.

Synonyms: MAP2K2, MEK2, MKK2, PRKMK2, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2
NCBI Accession NP_109587
UniProt P36507
Pathways MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-MAP2K2 Antibody Target Details MAP2K2 Handling References for anti-MAP2K2 antibody (ABIN1882178) Images back to top
Application Notes WB: 1:1000,IF: 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-MAP2K2 Antibody Target Details MAP2K2 Application Details References for anti-MAP2K2 antibody (ABIN1882178) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-MAP2K2 antibody (ABIN1882178)

Product Details anti-MAP2K2 Antibody Target Details MAP2K2 Application Details Handling Images back to top
Product cited in:

Burroughs, Oh, Barrett, DiAugustine et al.: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, 2003

Tran, Maurer, Nagamine: "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7177-88, 2003

Li, Junttila, Han, Kähäri, Westermarck: "p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2." in: Cancer research, Vol. 63, Issue 13, pp. 3473-7, 2003

Li, Inoki, Vacratsis, Guan: "The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13663-71, 2003

Liu, Jana, Dasgupta, Koka, He, Wood, Pahan: "Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia." in: The Journal of biological chemistry, Vol. 277, Issue 42, pp. 39312-9, 2002

Images

Product Details anti-MAP2K2 Antibody Target Details MAP2K2 Application Details Handling References for anti-MAP2K2 antibody (ABIN1882178) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibody (ABIN1882178) MEK2 (MAP2K2) Antibody (N-term) (ABIN1882178) western blot analysis in Hela,MCF-7,rat...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibody (ABIN1882178) MEK2 (MAP2K2) Antibody (N-term) (ABIN1882178) western blot analysis in Hela,MCF-7,rat...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibody (ABIN1882178) All lanes : Anti-MEK2 (MAP2K2) Antibody (N-term) at 1:1000 dilution Lane 1: Hela whol...