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|Antigen||Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MAP2K6 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-MAP2K6 AntibodyTarget Details MAP2K6 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human MEK6 around the phosphorylation site of Ser202|
Target Details MAP2K6Product Details anti-MAP2K6 Antibody Application Details Handling Images back to top
|Alternative Name||Mek6 (MAP2K6 Antibody Abstract)|
Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Synonyms: MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK6, MEK6, Mitogen Activated Protein Kinase Kinase 6, MKK 6, MKK6, PRKMK6, SAPKK3, Dual specicity mitogen activated protein kinase kinase 6, MKK 6, Dual specicity mitogen activated protein kinase kinase 6, EC 220.127.116.11, MP2K6_HUMAN.
|Research Area||Immunology, Innate Immunity, Tyrosine Kinases, Kinases/Phosphatases|
|Pathways||MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades|
Application DetailsProduct Details anti-MAP2K6 Antibody Target Details MAP2K6 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAP2K6 Antibody Target Details MAP2K6 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-MAP2K6 Antibody Target Details MAP2K6 Application Details Handling back to top