anti-Human MAP3K5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP3K5 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
  • ASK1
  • MAPKKK5
  • MEKK5
  • mitogen-activated protein kinase kinase kinase 5
  • MUD21.11
  • MUD21_11
  • 7420452D20Rik
  • ASK
  • Mekk5
  • Ask1
  • RGD1306565
  • mitogen-activated protein kinase kinase kinase 5
  • MAP3K5
  • MAPKKK5
  • Map3k5
  • map3k5
Epitope
C-Term
70
58
37
19
19
15
15
15
14
13
10
7
6
6
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
397
169
95
6
1
1
1
1
1
1
Host
Rabbit
375
28
Clonality
Polyclonal
Conjugate
This MAP3K5 antibody is un-conjugated
12
12
11
6
6
6
5
5
5
5
5
5
5
5
5
5
5
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
303
156
136
81
65
43
22
14
11
8
4
3
2
1
1
Supplier
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Catalog No. ABIN615252
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.8140135 ABIN683128 IF (p) IHC (p) WB Rabbit IgG AA 825-875, pThr845 Log in to see Polyclonal 1
12.8140135 ABIN461897 ICC IHC (p) ELISA WB Rabbit C-Term Log in to see Polyclonal 0
12.8140135 ABIN461898 IHC (p) ELISA WB Rabbit N-Term Log in to see Polyclonal 0
12.8140135 ABIN498823 IHC (p) Rabbit pSer966 Log in to see Polyclonal 0
12.8140135 ABIN498822 IHC (p) WB Rabbit pSer83 Log in to see Polyclonal 0
12.8140135 ABIN683098 IF (p) IHC (p) WB Rabbit IgG pSer967 Log in to see Polyclonal 0
12.8140135 ABIN682798 IF (p) IHC (p) WB Rabbit IgG pSer966 Log in to see Polyclonal 0
12.8140135 ABIN498912 IHC (p) Rabbit Log in to see Polyclonal 0
12.8140135 ABIN498913 IHC (p) Rabbit Log in to see Polyclonal 0
12.8140135 ABIN615253 EIA IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
12.8140135 ABIN4281871 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 0
12.8140135 ABIN5075149 IHC (p) Rabbit IgG Log in to see Polyclonal 0
12.8140135 ABIN5075148 IHC (p) Rabbit IgG Log in to see Polyclonal 0
12.8140135 ABIN4281873 IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
12.8140135 ABIN4281874 IHC IHC (p) WB Rabbit pSer83 Log in to see Polyclonal 0
12.8140135 ABIN4281872 IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN1496745 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 Log in to see 2E4 0
1 ABIN196914 IHC (p) WB Rabbit pSer966 Log in to see Polyclonal 4
1 ABIN197310 IF IHC (p) WB Rabbit Ser83 Log in to see Polyclonal 3
1 ABIN197326 IF IHC (p) WB Rabbit Ser966 Log in to see Polyclonal 4

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antibodies
Epitope C-Term
(70), (58), (37), (19), (19), (15), (15), (15), (14), (13), (10), (7), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(397), (169), (95), (6), (1), (1), (1), (1), (1), (1)
Host Rabbit
(375), (28)
Clonality
Polyclonal
Conjugate This MAP3K5 antibody is un-conjugated
(12), (12), (11), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(303), (156), (136), (81), (65), (43), (22), (14), (11), (8), (4), (3), (2), (1), (1)
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Product Details anti-MAP3K5 Antibody

Target Details MAP3K5 Application Details Handling Images
Specificity This antibody reacts to MAP Kinase Kinase Kinase 5 (MEKK5/ASK1) (MAP3K5).
Purification Immunoaffinity Chromatography
Immunogen MAP3K5 antibody was raised against synthetic peptide - KLH conjugated

Target Details MAP3K5

Product Details anti-MAP3K5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MEKK5 / ASK1 (MAP3K5 Antibody Abstract)
Background MEKK5, also known as ASK1 for apoptosis signal-regulating kinase-1, is a MAP3K type protein kinase and a member of the JNK and p38 MAP kinase signaling pathways. The protein contains a centrally located protein kinase domain, a N-terminal extension that includes binding regions for the Fas-associated adapter protein Daxx and the redox-sensing enzyme thioredoxin, and a C-terminal extension that binds members of the TNFR-associated factor (TRAF) family. MEKK5 regulates the JNK cascade by phosphorylating MKK4/MAP2K4 and p38 cascades by phosphorylating MEK3/MAP2K3 and MKK6/MAP2K6. MEKK5 has been shown to be activated by oxidant stress, tumor necrosis factor (TNF) via TRAF2 and Fas via Daxx. MEKK5 also can be activated by Fas-Daxx in a kinase-independent apoptotic pathway.Synonyms: Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, Mitogen-activated protein kinase kinase kinase 5
Gene ID 4217
NCBI Accession NP_005914
UniProt Q99683
Pathways MAPK Signaling, Positive Regulation of Endopeptidase Activity, Unfolded protein response

Application Details

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-MAP3K5 Antibody Target Details MAP3K5 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibody (ABIN615252) Immunocytochemistry of ASK1 in A431 cells with at 2 µg/ml.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibody (ABIN615252) Human Heart (formalin-fixed, paraffin-embedded) stained with MAP3K5at 5 µg/ml followe...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibody (ABIN615252) Human Pancreas (formalin-fixed, paraffin-embedded) stained with MAP3K5at 5 µg/ml foll...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibody (ABIN615252) Western blot analysis of ASK1 in SW1353 cell lysate with at (A) 0.5, (B) 1, and (C) 2...