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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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3.2595015 | ABIN2792184 | WB | Rabbit | C-Term | Log in to see | Polyclonal | 1 | |||
3.2595015 | ABIN926915 | IHC WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN5551610 | IHC (fro) WB | Rabbit | IgG | pThr180, pTyr182 | Log in to see | Polyclonal | 0 | ||
1 | ABIN214794 | IHC (p) WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN203076 | WB | Rabbit | IgG | C-Term | Log in to see | Polyclonal | 0 | ||
1 | ABIN319104 | WB | Rabbit | IgG | pThr180, pTyr182 | Log in to see | Polyclonal | 1 | ||
1 | ABIN5551337 | IHC (fro) IP WB | Rabbit | IgG | AA 341-360 | Log in to see | Polyclonal | 0 | ||
1 | ABIN319100 | WB | Rabbit | IgG | pThr202, pTyr204 | Log in to see | Polyclonal | 0 | ||
1 | ABIN227260 | IHC WB | Rabbit | pThr180, pTyr182 | Log in to see | Polyclonal | 0 | |||
1 | ABIN1911924 | IP WB | Rabbit | IgG | AA 1-50 | Log in to see | Polyclonal | 0 | ||
1 | ABIN1911926 | IP WB | Rabbit | IgG | AA 300-360, C-Term | Log in to see | Polyclonal | 0 | ||
1 | ABIN307668 | IP ELISA WB | Rabbit | AA 347-360 | Log in to see | Polyclonal | 0 | |||
1 | ABIN1102944 | IP IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN2959838 | IHC WB | Rabbit | IgG | pThr180, pTyr182 | Log in to see | Polyclonal | 0 | ||
1 | ABIN302107 | IP WB | Rabbit | AA 341-360 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Mitogen-Activated Protein Kinase 14 (MAPK14) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Cow (Bovine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This MAPK14 antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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1 reference available |
Supplier | Log in to see |
Product Details anti-MAPK14 AntibodyTarget Details MAPK14 Application Details Handling References for anti-MAPK14 antibody (ABIN2792183) Images |
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Sequence | YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES |
Predicted Reactivity | Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100% |
Characteristics | This is a rabbit polyclonal antibody against MAPK14. It was validated on Western Blot and immunohistochemistry. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK14 |
Target Details MAPK14Product Details anti-MAPK14 Antibody Application Details Handling References for anti-MAPK14 antibody (ABIN2792183) Images back to top |
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Antigen | |
Alternative Name | MAPK14 (MAPK14 Antibody Abstract) |
Background |
MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Alias Symbols: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA Protein Interaction Partner: MAPKAPK2, ATF2, PDX1, UBC, MARCKSL1, MAP2K3, MAPK14, ATF6, TCEAL1, USP11, PTPN11, OXCT1, NME1, WDR1, HSPD1, TYMS, ADSS, IQGAP1, MKNK1, MAPKAPK3, CNBP, AKT1, CCDC8, OBSL1, RRP1B, RPS6KA4, SRPK1, MAP2K6, MAPK11, NEB, MAZ, MKNK2, EEF2, DUSP9, ZFP36L1, ADRB2, Protein Size: 360 |
Molecular Weight | 41 kDa |
Gene ID | 1432 |
NCBI Accession | NM_001315, NP_001306 |
UniProt | Q16539 |
Pathways | MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling |
Application DetailsProduct Details anti-MAPK14 Antibody Target Details MAPK14 Handling References for anti-MAPK14 antibody (ABIN2792183) Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 360 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details References for anti-MAPK14 antibody (ABIN2792183) Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-MAPK14 antibody (ABIN2792183)Product Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Handling Images back to top |
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Background publications |
Alemán, Schierloh, de la Barrera, Musella, Saab, Baldini, Abbate, Sasiain: "Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients." in: Infection and immunity, Vol. 72, Issue 9, pp. 5150-8, 2004 |
ImagesProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Handling References for anti-MAPK14 antibody (ABIN2792183) back to top |
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Supplier Images |