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|Antigen||Mitogen-Activated Protein Kinase 14 (MAPK14) Antibodies|
|Epitope||pThr180, pTyr182 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MAPK14 antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-MAPK14 AntibodyTarget Details MAPK14 Application Details Handling Images
|Specificity||The antibody recognizes 43 kDa phosphorylated p38 (Thr180/Tyr182) MAP kinase|
|Immunogen||Synthetic phospho-peptide surrounding amino acid Thr180/Tyr182 of human p38 MAP kinase.|
|Plasmids, Primers & others|
Target Details MAPK14Product Details anti-MAPK14 Antibody Application Details Handling Images back to top
|Alternative Name||MAP Kinase p38 alpha / MAPK14 (MAPK14 Antibody Abstract)|
|Background||P38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha|
|Pathways||MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling|
Application DetailsProduct Details anti-MAPK14 Antibody Target Details MAPK14 Handling Images back to top
Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 mg/mL. Immunohistochemistry: 10-20 mg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Images back to top
|Buffer||PBS containing 50 % Glycerol, 1 % BSA as stabilizer and 0.02 % Thimerosal as preservative.|
|Precaution of Use||This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||-20 °C/-80 °C|
|Storage Comment||Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.|
ImagesProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Handling back to top