Get this product for free
Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN3023294 | ICC FACS IP WB | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
|
---|---|
Antigen | Mitogen-Activated Protein Kinase 14 (MAPK14) Antibodies |
Epitope | AA 301-330 Alternatives |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This MAPK14 antibody is un-conjugated Alternatives |
Application |
Flow Cytometry (FACS), Western Blotting (WB)
Alternatives
|
Supplier | Log in to see |
Product Details anti-MAPK14 AntibodyTarget Details MAPK14 Application Details Handling Images |
|
Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
Immunogen | This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from human MAPK14. |
Isotype | Ig Fraction |
Target Details MAPK14Product Details anti-MAPK14 Antibody Application Details Handling Images back to top |
|
Antigen | |
Alternative Name | MAPK14 (MAPK14 Antibody Abstract) |
Background | MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. |
Molecular Weight | 41 kDa |
Gene ID | 1432 |
UniProt | Q16539 |
Pathways | MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling |
Application DetailsProduct Details anti-MAPK14 Antibody Target Details MAPK14 Handling Images back to top |
|
Application Notes |
For FACS starting dilution is: 1:25 For WB starting dilution is: 1:2000 |
Restrictions | For Research Use only |
HandlingProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Images back to top |
|
Format | Liquid |
Buffer | Supplied in PBS with 0.09 % (W/V) sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C,-20 °C |
Storage Comment | Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
ImagesProduct Details anti-MAPK14 Antibody Target Details MAPK14 Application Details Handling back to top |
|
Supplier Images |