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|Antigen||Mitogen-Activated Protein Kinase 6 (MAPK6) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MAPK6 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-MAPK6 AntibodyTarget Details MAPK6 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human MAPK6/ERK3|
Target Details MAPK6Product Details anti-MAPK6 Antibody Application Details Handling Images back to top
|Alternative Name||Mapk6/Erk3 (MAPK6 Antibody Abstract)|
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
Synonyms: ERK-3, ERK3, ERK 3, ERK-3, Extracellular signal regulated kinase 3, Extracellular signal regulated kinase p97, Extracellular signal-regulated kinase 3, MAP kinase 6, MAP kinase isoform p97, MAPK 6, MAPK6, Mitogen activated protein kinase 6, Mitogen-activated protein kinase 6, MK06_HUMAN, p97 MAPK, p97-MAPK, PRKM6, Protein kinase mitogen activated 5, Protein kinase mitogen activated 6.
|Pathways||MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C|
Application DetailsProduct Details anti-MAPK6 Antibody Target Details MAPK6 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-MAPK6 Antibody Target Details MAPK6 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
ImagesProduct Details anti-MAPK6 Antibody Target Details MAPK6 Application Details Handling back to top