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anti-Human MAPK9 Antibodies:
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Human Polyclonal MAPK9 Primary Antibody for IHC (p), WB - ABIN1882172
Gupta, Barrett, Whitmarsh, Cavanagh, Sluss, Dérijard, Davis: Selective interaction of JNK protein kinase isoforms with transcription factors. in The EMBO journal 1996
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Human Polyclonal MAPK9 Primary Antibody for ELISA, WB - ABIN4327970
Leppä, Bohmann: Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. in Oncogene 1999
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
mitogen-activated protein kinase 9
, Jun kinase
, MAP kinase 9
, MAPK 9
, c-Jun N-terminal kinase 2
, c-Jun kinase 2
, stress-activated protein kinase 1a
, stress-activated protein kinase JNK2
, JNK/SAPK alpha
, mitogen activated protein kinase 9
, protein kinase, mitogen-activated 9
, stress activated protein kinase alpha II
, janus kinase 2
, c-JUN amino-terminal kinase-2 alpha1