anti-Human MAPT antibody for Immunohistochemistry

Recommended MAPT Antibody (supplied by: Log in to see )

Antigen
Microtubule-Associated Protein tau (MAPT) Antibodies
  • DDPAC
  • FTDP-17
  • MAPTL
  • MSTD
  • MTBT1
  • MTBT2
  • PPND
  • TAU
  • AI413597
  • AW045860
  • Mtapt
  • Tau
  • RNPTAU
  • pTau
  • tau
  • xtp
  • MAPT
  • PHF-tau
  • slc6a6
  • taut
  • wu:fc26e12
  • microtubule associated protein tau
  • microtubule-associated protein tau
  • microtubule associated protein tau S homeolog
  • Microtubule-associated protein tau
  • solute carrier family 6 (neurotransmitter transporter), member 6b
  • MAPT
  • Mapt
  • mapt.S
  • LOC5580230
  • CpipJ_CPIJ013260
  • tau
  • slc6a6b
Epitope
Middle Region
51
46
43
41
38
38
37
36
30
30
29
29
21
19
17
17
17
17
16
14
11
11
11
10
10
10
10
10
9
9
9
9
9
8
8
7
6
6
6
6
6
6
5
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
1103
690
664
123
46
43
42
37
25
17
12
9
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
1005
139
12
7
Clonality
Polyclonal
Conjugate
This MAPT antibody is un-conjugated
27
12
11
7
6
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
1055
412
332
152
99
66
59
30
18
14
13
12
12
12
9
4
4
2
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Catalog No. ABIN2783223
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.312961 ABIN2707141 IHC WB Rabbit pSer529 Log in to see Polyclonal 0
9.312961 ABIN2705274 IC IF IHC WB Rabbit C-Term, pSer356 Log in to see Polyclonal 0
9.312961 ABIN257610 ICC IF IHC (p) IHC WB Rabbit pSer262 Log in to see Polyclonal 0
9.312961 ABIN257613 IHC (p) IHC WB Rabbit pThr181 Log in to see Polyclonal 0
9.312961 ABIN1531989 IHC ELISA WB Rabbit IgG AA 641-690, pSer673 Log in to see Polyclonal 0
9.312961 ABIN1531993 IHC ELISA Rabbit IgG AA 496-545, pThr529 Log in to see Polyclonal 0
9.312961 ABIN1869091 ICC IHC WB Rabbit IgG AA 130-386 Log in to see Polyclonal 0
9.312961 ABIN257611 IHC (p) IHC WB Rabbit pSer396 Log in to see Polyclonal 0
9.312961 ABIN1870397 IHC WB Rabbit IgG pSer396 Log in to see Polyclonal 0
9.312961 ABIN1870400 IHC WB Rabbit IgG pThr205 Log in to see Polyclonal 0
9.312961 ABIN1870403 IF IHC WB Rabbit IgG pSer404 Log in to see Polyclonal 0
9.312961 ABIN1870410 IHC WB Rabbit IgG pThr181 Log in to see Polyclonal 0
9.312961 ABIN1870407 IF IHC WB Rabbit IgG pSer262 Log in to see Polyclonal 0
9.312961 ABIN1870414 IHC WB Rabbit IgG pThr231 Log in to see Polyclonal 0
9.312961 ABIN1873640 IHC WB Rabbit IgG Log in to see Polyclonal 0
9.312961 ABIN1742567 ICC IP IHC WB Mouse IgG2a AA 3-214 Log in to see 248E5 2
9.312961 ABIN1585350 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
9.312961 ABIN957792 IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
9.312961 ABIN3031796 IF IHC ELISA WB Rabbit Ig Fraction AA 677-707 Log in to see Polyclonal 0
9.312961 ABIN3031794 IHC ELISA WB Rabbit Ig Fraction AA 699-728 Log in to see Polyclonal 0

General

Antigen Microtubule-Associated Protein tau (MAPT) Antibodies
Epitope Middle Region
(51), (46), (43), (41), (38), (38), (37), (36), (30), (30), (29), (29), (21), (19), (17), (17), (17), (17), (16), (14), (11), (11), (11), (10), (10), (10), (10), (10), (9), (9), (9), (9), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(1103), (690), (664), (123), (46), (43), (42), (37), (25), (17), (12), (9), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1005), (139), (12), (7)
Clonality
Polyclonal
Conjugate This MAPT antibody is un-conjugated
(27), (12), (11), (7), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(1055), (412), (332), (152), (99), (66), (59), (30), (18), (14), (13), (12), (12), (12), (9), (4), (4), (2)
Pubmed 1 reference available
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Product Details anti-MAPT Antibody

Target Details MAPT Application Details Handling References for anti-MAPT antibody (ABIN2783223) Images
Blocking Peptide Blocking peptide for this product available: ABIN979811
Sequence RGAAPPGQKG QANATRIPAK TPPAPKTPPS SGEPPKSGDR SGYSSPGSPG
Predicted Reactivity Human: 100%, Mouse: 86%, Pig: 79%, Rat: 86%
Characteristics This is a rabbit polyclonal antibody against MAPT. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MAPT
Plasmids, Primers & others

Target Details MAPT

Product Details anti-MAPT Antibody Application Details Handling References for anti-MAPT antibody (ABIN2783223) Images back to top
Antigen
Alternative Name MAPT (MAPT Antibody Abstract)
Background MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Alias Symbols: DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Protein Interaction Partner: Ywhaz, Prkaca, STUB1, PHGK, SRC, PRKAR1A, GSK3B, FYN, DCTN1, CSNK1A1, CDK2, AKT1, ABL1, YWHAQ, SGK1, MARK2, MARCH7, TUBB3, TUBA1B, UBC, TUBA4A, MARK4, PEG10, MARK3, MARK1, MAPK13, MAPK11, MAPK8, mapk14, Mapk12, LIMS1, HSPA1A, PPP5C, PPP2R4, CAPN2, PKN1, H
Protein Size: 441
Molecular Weight 46 kDa
Gene ID 4137
NCBI Accession NM_005910, NP_005901
Pathways MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size

Application Details

Product Details anti-MAPT Antibody Target Details MAPT Handling References for anti-MAPT antibody (ABIN2783223) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 441 AA

Restrictions For Research Use only

Handling

Product Details anti-MAPT Antibody Target Details MAPT Application Details References for anti-MAPT antibody (ABIN2783223) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MAPT antibody (ABIN2783223)

Product Details anti-MAPT Antibody Target Details MAPT Application Details Handling Images back to top
Background publications

Reynolds, Lukas, Berry, Binder: "Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms." in: Biochemistry, Vol. 45, Issue 13, pp. 4314-26, 2006

Images

Product Details anti-MAPT Antibody Target Details MAPT Application Details Handling References for anti-MAPT antibody (ABIN2783223) back to top
Supplier Images
Western Blotting (WB) image for anti-Microtubule-Associated Protein tau (MAPT) (Middle Region) antibody (ABIN2783223) WB Suggested Anti-MAPT Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...
Western Blotting (WB) image for anti-Microtubule-Associated Protein tau (MAPT) (Middle Region) antibody (ABIN2783223) WB Suggested Anti-MAPT Antibody Positive Control: Lane 1: 10ug N2A expressed huma...
Western Blotting (WB) image for anti-Microtubule-Associated Protein tau (MAPT) (Middle Region) antibody (ABIN2783223) Researcher: Max Holzer, Paul Flechsig Institut of Brain Research, University of Leipz...
Immunohistochemistry (IHC) image for anti-Microtubule-Associated Protein tau (MAPT) (Middle Region) antibody (ABIN2783223) Sample Type : A: Transgenic hTau P301L mouse cortex B: Tau-Ko mouse cortex C: WT m...