anti-Human MCL-1 antibody for Immunocytochemistry
Recommended MCL-1 Antibody (supplied by: Log in to see )
- Antigen
-
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
show synonyms for this antigen- AW556805
- Mcl-1
- BCL2L3
- EAT
- MCL1-ES
- MCL1L
- MCL1S
- TM
- bcl2-L-3
- mcl1/EAT
- mcl-1
- myeloid cell leukemia sequence 1
- MCL1, BCL2 family apoptosis regulator
- Mcl1
- MCL1
- Reactivity
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Human
Alternatives - Host
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Mouse
Alternatives - Clonality
- Conjugate
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This MCL-1 antibody is un-conjugated
Alternatives - Application
-
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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Catalog No. ABIN969485
$ 345.40
Plus shipping costs $45.00
Plus shipping costs $45.00
| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 25.965536 | ABIN4333158 | ICC IF WB | Rabbit | Center | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN2855261 | ICC IF IHC (p) WB | Rabbit | IgG | Center | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN2869169 | ELISA ICC IHC WB | Mouse | IgG1 | Log in to see | 8C6-8C6D4B1 | 1 | |||
| 1 | ABIN214512 | ICC IHC (p) WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN1869117 | ICC IHC WB | Rabbit | IgG | AA 6-328 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN207760 | ICC WB | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN207776 | ICC WB | Rabbit | Internal Region | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN1736826 | ICC IHC (p) WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN5627289 | ELISA ICC IF WB | Rabbit | IgG | AA 220-270 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN1030511 | ICC ELISA WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN1031455 | ICC ELISA WB | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN1030997 | ICC ELISA WB | Rabbit | Middle Region | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN4333157 | ELISA ICC IF IHC IHC (fro) IHC (p) WB | Mouse | IgG1 | Log in to see | 8C6D4B1 | 0 | |||
| 1 | ABIN4333167 | ICC IF IHC IHC (p) WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN4333174 | ELISA ICC IF WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
| 1 | ABIN4333172 | ELISA ICC IF WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
| 1 | ABIN4333171 | ELISA ICC IF WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
| 1 | ABIN5681489 | ELISA ICC IF IHC IHC (fro) IHC (p) WB | Mouse | IgG1 | Log in to see | 8C6 | 0 | |||
| 1 | ABIN4333163 | ICC IF IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
| 1 | ABIN4333176 | ELISA ICC IF IHC (fro) IHC (p) WB | Alexa Fluor 405 | Mouse | IgG1 | Log in to see | 8C6D4B1 | 0 |
General |
|
|---|---|
| Antigen | Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies |
| Reactivity | Human Alternatives |
| Host | Mouse Alternatives |
| Clonality (Clone) | |
| Conjugate | This MCL-1 antibody is un-conjugated Alternatives |
| Application |
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives
|
|
2 references available |
| Supplier | Log in to see |
Product Details anti-MCL-1 AntibodyTarget Details MCL-1 Application Details Handling References for anti-MCL-1 antibody (ABIN969485) Images |
|
| Purification | Purified |
| Immunogen | Purified recombinant fragment of human MCL-1 expressed in E. Coli. |
| Clone | 8C6 |
| Isotype | IgG1 |
Target Details MCL-1Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 antibody (ABIN969485) Images back to top |
|
| Antigen | |
| Alternative Name | MCL-1 (MCL1 Antibody Abstract) |
| Background | Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate. |
| Molecular Weight | 37 kDa |
| Gene ID | 4170 |
| HGNC | 4170 |
| Pathways | MAPK Signaling |
Application DetailsProduct Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 antibody (ABIN969485) Images back to top |
|
| Application Notes | ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 antibody (ABIN969485) Images back to top |
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| Format | Liquid |
| Buffer | PBS containing 0.03 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | 4 °C,-20 °C |
| Storage Comment | 4°C, -20°C for long term storage |
References for anti-MCL-1 antibody (ABIN969485)Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top |
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| Product cited in: |
Richert, Schwertfeger, Ryder, Anderson: "An atlas of mouse mammary gland development." in: Journal of mammary gland biology and neoplasia, Vol. 5, Issue 2, pp. 227-41, 2001 MacLachlan, Hébert: "Statement concerning euthanasia and physician-assisted suicide. Ethics Committee of the College of Family Physicians of Canada." in: Canadian family physician Médecin de famille canadien, Vol. 46, pp. 254-6, 264-7, 2000 |
ImagesProduct Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 antibody (ABIN969485) back to top |
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| Supplier Images |
Figure 1: Confocal immunofluorescence analysis of HepG2 cells using MCL1 mouse mAb (g...
Figure 2: Immunohistochemical analysis of paraffin-embedded human lymphnode tissues u...
Figure 3: Western blot analysis using MCL1 mouse mAb against Hela (1), BCBL-1 (2), Ju...
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