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|Antigen||Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies|
|Epitope||AA 210-248 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MCL-1 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-MCL-1 AntibodyTarget Details MCL-1 Application Details Handling References for anti-MCL-1 antibody (ABIN675369) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human MCL1|
Target Details MCL-1Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 antibody (ABIN675369) Images back to top
|Alternative Name||Mcl1 (MCL1 Antibody Abstract)|
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Subcellular location: Helical
Synonyms: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, MCL1
Application DetailsProduct Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 antibody (ABIN675369) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 antibody (ABIN675369) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-MCL-1 antibody (ABIN675369)Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
|Product cited in:||
Wang, Zhang, Wang, Wang, Wang, Wu, Wu, Zhang, Zhang: "A small hairpin RNA targeting myeloid cell leukemia-1 enhances apoptosis in host macrophages infected with Mycobacterium tuberculosis." in: Journal of microbiology (Seoul, Korea), Vol. 54, Issue 4, pp. 330-7, 2016 (Sample species: Mouse (Murine)).
Chen, Xie, Zhao, Wang, Bai, Yin, Jiang, Xie, Jia, Huang et al.: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, 2014 Method employed by authors: Western Blotting (WB), Western Blotting (WB) (Sample species: Human).
Zhang, Liu, Xia, Zhang, Zhang, Zhao, Chao, Jiang, Jiang: "Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells." in: International journal of molecular medicine, Vol. 33, Issue 1, pp. 151-9, 2013 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, 2013 Method employed by authors: Western Blotting (WB) (Sample species: Human).
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