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anti-Human p38 Antibodies:
anti-Rat (Rattus) p38 Antibodies:
anti-Mouse (Murine) p38 Antibodies:
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Human Polyclonal p38 Primary Antibody for IF (cc), IF (p) - ABIN671241
Li, Dong, Song, Xu, Liu, Song: Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling. in Chemico-biological interactions 2014
Show all 12 Pubmed References
Human Polyclonal p38 Primary Antibody for ELISA, ICC - ABIN6267706
Liu, Zheng, Zhang, Wang, Yang, Bai, Dai: Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells. in Neurochemical research 2017
Show all 7 Pubmed References
Human Polyclonal p38 Primary Antibody for IF (p), IHC (p) - ABIN710141
Zhao, Liu, Liu, Han, Zhao: Betulin attenuates lung and liver injuries in sepsis. in International immunopharmacology 2015
Show all 6 Pubmed References
Human Polyclonal p38 Primary Antibody for ELISA, ICC - ABIN6263958
Zou, Xiang, Wang, Peng, Wei: Oregano Essential Oil Improves Intestinal Morphology and Expression of Tight Junction Proteins Associated with Modulation of Selected Intestinal Bacteria and Immune Status in a Pig Model. in BioMed research international 2017
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Human Monoclonal p38 Primary Antibody for ICS - ABIN1177122
Brunet, Pouysségur: Identification of MAP kinase domains by redirecting stress signals into growth factor responses. in Science (New York, N.Y.) 1996
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Human Polyclonal p38 Primary Antibody for IHC, IHC (p) - ABIN152964
Ito, Miyado, Nakagawa, Muraki, Imai, Yamakawa, Qin, Hosoi, Saito, Takahashi: Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells. in Molecular human reproduction 2010
Show all 5 Pubmed References
Human Polyclonal p38 Primary Antibody for ELISA, ICC - ABIN6255833
Jin, Han, Yang, Hu, Liu, Zhao: 11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury. in Molecular medicine reports 2017
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Human Monoclonal p38 Primary Antibody for ICS - ABIN1177120
Han, Lee, Bibbs, Ulevitch: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. in Science (New York, N.Y.) 1994
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Human Monoclonal p38 Primary Antibody for ICS - ABIN1177124
Winston, Chan, Johnson, Riches: Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages. in Journal of immunology (Baltimore, Md. : 1950) 1997
Show all 3 Pubmed References
Data show that miR (show MLXIP Antibodies)-625-3p induces oxaliplatin resistance by abrogating MAP2K6 (show MAP2K6 Antibodies)-p38 (show CRK Antibodies)-regulated apoptosis and cell cycle control networks.
Immune profiling of human prostate epithelial cells in health and pathology determined by expression of p38 (show CRK Antibodies)/TRAF-6 (show TRAF6 Antibodies)/ERK (show EPHB2 Antibodies) MAP kinases pathways has been reported.
The cytotoxicity induced by EB1 (show MAPRE2 Antibodies) gene knockdown was due to the activation and generation of reactive oxygen species by p38 mitogen-activated protein kinase (show MAPK14 Antibodies)..this signaling cascade, however not nuclear factor-kappaB-mediated signaling, induced the expression of cyclooxygenase-2 (show PTGS2 Antibodies), a key effector of apoptotic death.
Data, including data using network analysis, suggest that angiotensinogen (AGT (show AGT Antibodies)), mitogen-activated protein kinase-14 (MAPK14 (show MAPK14 Antibodies)), and prothrombin (show F2 Antibodies) (F2) in placental villous tissues are core factors in early embryonic development; these studies involved proteomics and bioinformatics analysis of altered protein expression in placental villous tissue from early recurrent miscarriage patients in comparison to control tissues.
The role of p38 MAP kinase (show MAPK14 Antibodies) signaling in metastatic clear cell renal cell carcinoma (show MOK Antibodies)
Rhythmic luciferase activity from clock gene luciferase reporter cells lines was used to test the effect of p38 MAPK (show MAPK14 Antibodies) inhibition on clock properties as determined using the damped sine fit and Levenberg-Marquardt algorithm.Glioma treatment with p38 MAPK (show MAPK14 Antibodies) inhibitors may be more effective and less toxic if administered at the appropriate time of the day.
Hsp27 (show HSPB1 Antibodies) and P38MAPK (show MAPK14 Antibodies) could be used as prognostic factors in Esophageal squamous cell carcinoma.
High p38MAPK (show MAPK14 Antibodies) expression is associated with non-small cell lung cancer metastasis.
when the cells were treated with SB203580, an inhibitor of the p38 MAPK (show MAPK14 Antibodies) pathway, the osteogenic effects of Epo (show EPO Antibodies) on hPDLSCs and pPDLSCs were attenuated. In conclusion, Epo (show EPO Antibodies) may upregulate the bone formation ability of hPDLSCs and pPDLSCs via the p38 MAPK (show MAPK14 Antibodies) pathways
p38alpha (show MAPK14 Antibodies) and ATF2 (show ATF2 Antibodies) expression play a crucial role in the malignant phenotypes of ovarian tumor cells and are a markers of poor prognosis in patients with ovarian serous adenocarcinomas.
results suggest that ET-1 (show EDN1 Antibodies)-induced activation of proMMP-2 is mediated via cross-talk between NADPH oxidase (show NOX1 Antibodies)-PKCalpha (show PKCa Antibodies)-p(38)MAPK (show MAPK1 Antibodies) and NFkappaB-MT1MMP (show MMP14 Antibodies) signaling pathways along with a marked decrease in TIMP-2 (show TIMP2 Antibodies) expression in the cells
cross-talk between p(38)MAPK (show MAPK1 Antibodies) and Gialpha play a pivotal role for full activation of cPLA2 (show PLA2G4A Antibodies) during ET-1 (show EDN1 Antibodies) stimulation of pulmonary artery smooth muscle cells.
MAPK14 (show MAPK14 Antibodies) signalling pathway is largely involved in heat-induced sperm damage.
p38 MAPK (show MAPK14 Antibodies) is an early redox sensor in the laminar shear stress with hydrogen peroxide being a signaling mediator.
Blockade of p38 (show MAPK14 Antibodies) enhances chondrocyte phenotype in monolayer culture and may promote more efficient cartilage tissue regeneration for cell-based therapies.
p38 (show MAPK14 Antibodies) phosphorylation and MMP13 (show MMP13 Antibodies) expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.
These data suggest that the p38 (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.
findings support the hypothesis that ischemic factor stimulation of the blood-brain barrier Na-K-Cl cotransporter (show SLC12A1 Antibodies) involves activation of p38 (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) MAPKs
These data suggest a differential requirement of JNK1 (show MAPK8 Antibodies) and p38 MAPK (show MAPK14 Antibodies) in TNF (show TNF Antibodies) regulation of E2F1 (show E2F1 Antibodies). Targeted inactivation of JNK1 (show MAPK8 Antibodies) at arterial injury sites may represent a potential therapeutic intervention for ameliorating TNF (show TNF Antibodies)-mediated EC dysfunction.
p38 MAPK (MAPK14 (show MAPK14 Antibodies)) is redox-regulated in reactive oxygen species-dependent endothelial barrier dysfunction.
we have identified novel interaction between p38 MAPK (show MAPK14 Antibodies) and Runx2 (show RUNX2 Antibodies) enhances Runx2 (show RUNX2 Antibodies) transactivity, thus promoting vascular smooth muscle cells calcification
p38alpha (show MAPK14 Antibodies) MAPK (show MAPK1 Antibodies) maintains the expression of antioxidant genes in liver of young animals via NF-kappaBeta (show NFKB1 Antibodies) under basal conditions, whereas its long-term deficiency triggers compensatory up-regulation of antioxidant enzymes through NF-kappaBeta (show NFKB1 Antibodies).
the present findings suggested that artesunate may exert protective effects against cerebral ischemia/reperfusion injury through the suppression of oxidative and inflammatory processes, via activating Nrf2 (show NFE2L2 Antibodies) and downregulating ROSdependent p38 MAPK (show MAPK14 Antibodies) in mice.
Results show that the p38 MAPK (show MAPK14 Antibodies) signaling pathway could regulate mitochondria Abeta (show APP Antibodies) internalization by manipulating the expression of alpha7nAChR. Pretreatment of alpha7nAChR agonist could attenuate these biochemical changes which are tightly associated with Abeta1-42 induced apoptosis. Suggesting there is an endogenous, previously unrecognized cholinergic mechanism to control mitochondria functions and their apoptotic ...
Prdx1 (show PRDX1 Antibodies) knockout can aggravate the oxidative stress and lung injury by increasing the level of Reactive Oxygen Species (ROS (show ROS1 Antibodies)), and also activate P38 (show CRK Antibodies)/JNK (show MAPK8 Antibodies) signaling pathway.
P38 (show CRK Antibodies) kinase role in the inflammatory pain.CXCL13, upregulated by peripheral inflammation, acts on CXCR5 (show CXCR5 Antibodies) on dorsal root ganglia neurons and activates p38 (show CRK Antibodies), which increases Nav1.8 (show SCN10A Antibodies) current density and further contributes to the maintenance of inflammatory pain.
these findings indicate that BMS309403 reduces fatty acid-induced ER stress-associated inflammation in skeletal muscle by reducing p38 MAPK (show MAPK14 Antibodies) activation.
report insulin-like growth factor-II binding protein 1 (IGF2BP1 (show B4GALNT2 Antibodies)) as a novel interacting partner of p38 MAPK (show MAPK14 Antibodies).
These results were supported by the opposite outcomes observed for cells treated with A779 or DX600. Therefore, it was concluded that the ACE2 (show ACE2 Antibodies)-Ang (show ANG Antibodies)(17)-Mas (show MAS1 Antibodies) axis significantly inhibits pancreatitis by inhibition of the p38 MAPK (show MAPK14 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signaling pathway
results suggest that c-Jun (show JUN Antibodies), p38 MAPK (show MAPK14 Antibodies), PIK3CA (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies), and GSK3 signaling involved in the effect of miR (show MLXIP Antibodies)-203 on the proliferation of hepatocellular carcinoma cells.
P38 (show MAPK14 Antibodies) and JNK (show MAPK8 Antibodies) have opposing effects on persistence of in vivo leukocyte migration in zebrafish.
Adult zebrafish cardiomyocytes express active p38alpha (show MAPK14 Antibodies) MAPK (show MAPK1 Antibodies), which is switched off upon entry into mitosis.
Dkk3r regulates p38a (show MAPK14 Antibodies) phosphorylation to maintain Smad4 (show SMAD4 Antibodies) stability, in turn enabling the Smad2 (show SMAD2 Antibodies).Smad3a.Smad4 complex to form and activate the myf5 (show MYF5 Antibodies) promoter.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Csaids binding protein
, MAP kinase 14
, MAP kinase 2
, MAP kinase Mxi2
, MAP kinase p38 alpha
, MAPK 14
, MAX-interacting protein 2
, cytokine suppressive anti-inflammatory drug binding protein
, cytokine-supressive anti-inflammatory drug binding protein
, mitogen-activated protein kinase 14
, mitogen-activated protein kinase 14A
, mitogen-activated protein kinase p38 alpha
, p38 MAP kinase
, p38 mitogen activated protein kinase
, p38alpha Exip
, reactive kinase
, stress-activated protein kinase 2A
, cytokine suppressive anti-inflammatory drug binding protein 1
, mitogen activated protein kinase 14
, p38 MAP kinase alpha
, p38 MAPK
, p38 alpha
, tRNA synthetase cofactor p38
, MAP kinase 14A
, MAP kinase p38a
, MAPK 14A
, Mitogen-activated protein kinase p38a
, mitogen-activated protein kinase p38a