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Human p38 ELISA Kit for Cell ELISA - ABIN1981835
Han, Lee, Bibbs, Ulevitch: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. in Science (New York, N.Y.) 1994
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Human p38 ELISA Kit for Sandwich ELISA - ABIN625229
Brenner, Rosenhagen, Brandt, Schmitt, Jung, Schemmer, Schmidt, Mieth, Bruckner, Lichtenstern, Martin, Weigand, Hofer: Cell death biomarkers as early predictors for hepatic dysfunction in patients after orthotopic liver transplantation. in Transplantation 2012
Data suggest that in vitro-induction of CD8 (show CD8A ELISA Kits)+ Tregs depended in part on transforming growth factor beta 1 (TGF-beta1 (show TGFB1 ELISA Kits)) activation of p38 MAPK (show MAPK14 ELISA Kits) signaling, and that p38 MAPK (show MAPK14 ELISA Kits) could be a therapeutic target in ovarian cancer (OC) anti-tumor immunotherapy.
present study provides evidence that variations in GADD45B (show GADD45B ELISA Kits) rs2024144T, MAPK14 (show MAPK14 ELISA Kits) rs3804451A and GADD45A (show GADD45A ELISA Kits) rs581000C may predict platinum-based chemotherapy toxicity outcomes in patients with advanced non-small cell lung cancer
Gab1/SHP2 (show PTPN11 ELISA Kits)/p38MAPK (show MAPK14 ELISA Kits) signaling pathway and Ang-2 (show ANGPT2 ELISA Kits) have an essential role in regulating thrombin (show F2 ELISA Kits)-induced monocyte adhesion and vascular leakage
Studies suugest Wip1 (show PPM1D ELISA Kits) role in tumorigenesis through regulation of p53 (show TP53 ELISA Kits) and p38MAPK (show MAPK14 ELISA Kits) pathways.
Data show that Cx43 (show GJA1 ELISA Kits) was inhibited predominantly via IL-1beta (show IL1B ELISA Kits)-activated ERK1/2 (show MAPK1/3 ELISA Kits) and p38 MAP kinase (show MAPK14 ELISA Kits) cascades.
cyclophilin (show PPIA ELISA Kits)-dependent isomerisation of p38MAPK (show MAPK14 ELISA Kits) is an important novel mechanism in regulating p38MAPK (show MAPK14 ELISA Kits) phosphorylation and functions.
MEK2 (show MAP2K2 ELISA Kits) was essential for the phosphorylation of MKK3 (show MAP2K3 ELISA Kits)/MKK6 (show MAP2K6 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) that directly impacted on cyclin D1 (show CCND1 ELISA Kits) expression.
stress-induced activation of p38 MAPK (show MAPK14 ELISA Kits) and apoptosis in endothelial cells and established the link between the acid sphingomyelinase (show SMPD1 ELISA Kits)/ceramide and p38 MAPK (show MAPK14 ELISA Kits) pathways.
The results of this study suggest for the first time that cadmium induces MUC8 expression via TLR4 (show TLR4 ELISA Kits)-mediated ERK1/2 (show MAPK1/3 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) signaling pathway in human airway epithelial cells
These data suggested that t-BHP induced both apoptosis and necroptosis in endothelial cells which was mediated by ROS (show ROS1 ELISA Kits) and p38MAPK (show MAPK14 ELISA Kits). ROS (show ROS1 ELISA Kits) derived from NADPH oxidase (show NOX1 ELISA Kits) and mitochondria contributed to t-BHPL and t-BHPH-induced apoptosis and necroptosis, respectively
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.