anti-Monkey PAK2 antibody for Immunohistochemistry

Recommended PAK2 Antibody (supplied by: Log in to see )

Antigen
P21-Activated Kinase 2 (PAK2) Antibodies
  • PAK65
  • PAKgamma
  • gamma-PAK
  • 5330420P17Rik
  • A130002K10Rik
  • AI836325
  • D16Ertd269e
  • PAK-2
  • mKIAA4182
  • pak2
  • cb422
  • kinase
  • zgc:91798
  • wu:fb71h01
  • si:dz198m22.1
  • pak65
  • pakgamma
  • PAKI
  • Pak3
  • p21 (RAC1) activated kinase 2
  • p21 protein (Cdc42/Rac)-activated kinase 2
  • p21 protein (Cdc42/Rac)-activated kinase 2a
  • p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog
  • PAK2
  • Pak2
  • pak2a
  • pak2.S
Reactivity
Human, Monkey
212
120
114
9
7
1
Host
Mouse
195
17
Clonality
Monoclonal
Conjugate
This PAK2 antibody is un-conjugated
4
4
4
4
4
4
Application
ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
192
123
96
45
20
6
5
5
3
2
2
1
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Catalog No. ABIN2869426
$ 561.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.538242 ABIN1842653 ELISA IF/ICC IHC WB Mouse IgG1 Log in to see 0
8.538242 ABIN969338 ICC IHC ELISA WB Mouse IgG1 Log in to see 3B5 2
8.538242 ABIN932933 IF IHC ELISA WB Mouse IgG1 Log in to see 3B5 0
1 ABIN4343466 ELISA ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 3B5 0
1 ABIN4343465 ELISA ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 3B5 0
1 ABIN1578663 IF IHC ELISA WB Mouse Log in to see 0

General

Antigen P21-Activated Kinase 2 (PAK2) Antibodies
Reactivity Human, Monkey
(212), (120), (114), (9), (7), (1)
Host Mouse
(195), (17)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PAK2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
(192), (123), (96), (45), (20), (6), (5), (5), (3), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-PAK2 Antibody

Target Details PAK2 Application Details Handling References for anti-PAK2 antibody (ABIN2869426) Images
Purpose Purified Mouse Monoclonal Antibody
Characteristics Synonyms: Serine/threonine-protein kinase PAK 2, 2.7.11.1, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK-2p27, p27, PAK-2p34, p34, C-t-PAK2, PAK2
Purification Ascitic fluid
Immunogen

Immunogen: Purified recombinant fragment of PAK2 expressed in E. Coli.

Antigen Type: Recombinant Protein

Clone 3B5
Isotype IgG1
Plasmids, Primers & others

Target Details PAK2

Product Details anti-PAK2 Antibody Application Details Handling References for anti-PAK2 antibody (ABIN2869426) Images back to top
Antigen
Alternative Name PAK2 (PAK2 Antibody Abstract)
Background

Other Names: Serine/threonine-protein kinase PAK 2, 2.7.11.1, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK-2p27, p27, PAK-2p34, p34, C-t-PAK2, PAK2

Description: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Molecular Weight 58043
Gene ID 5062
UniProt Q13177
Pathways MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha

Application Details

Product Details anti-PAK2 Antibody Target Details PAK2 Handling References for anti-PAK2 antibody (ABIN2869426) Images back to top
Application Notes The suggested dilution is: Western Bloting: = 1:500 - 2000. Immunohistochemistry: = 1:200 - 1000. Immunofluorescence: = 1:200 - 1000.
Restrictions For Research Use only

Handling

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details References for anti-PAK2 antibody (ABIN2869426) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-PAK2 antibody (ABIN2869426)

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details Handling Images back to top
Background publications

Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, 2007

Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, 2004

Images

Product Details anti-PAK2 Antibody Target Details PAK2 Application Details Handling References for anti-PAK2 antibody (ABIN2869426) back to top
Supplier Images
Western Blotting (WB) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN2869426) Figure 1: Western blot analysis using PAK2 mouse mAb against Hela (1), Jurkat (2), A5...
Immunohistochemistry (IHC) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN2869426) Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) ...
Immunofluorescence (IF) image for anti-P21-Activated Kinase 2 (PAK2) antibody (ABIN2869426) Figure 3: Confocal immunofluorescence analysis of Hela cells using PAK2 mouse mAb (gr...