anti-Mouse (Murine) Paxillin antibody for Flow Cytometry
Recommended Paxillin Antibody
- Antigen
-
Paxillin (PXN) Antibodies
show synonyms for this antigen- AW108311
- AW123232
- Pax
- CG18061
- CG18576
- CG31794
- CT40481
- CT42454
- DPaxillin
- DPxn
- DPxn37
- Dmel\\CG31794
- Dpax
- DpaxA
- PDLP
- dPax
- pax
- wu:fw71f12
- PXN
- LOC100220858
- paxillin
- Paxillin
- paxillin S homeolog
- paxillin a
- PXN
- Pxn
- Pax
- pxn.S
- pxna
- LOC696336
- pxn
- Reactivity
-
Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This Paxillin antibody is un-conjugated
Alternatives - Application
-
Flow Cytometry (FACS)
Alternatives - Options
Available images
General |
|
|---|---|
| Antigen | Paxillin (PXN) Antibodies |
| Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality (Clone) | |
| Conjugate | This Paxillin antibody is un-conjugated Alternatives |
| Application |
Flow Cytometry (FACS)
Alternatives
|
|
4 references available |
| Supplier | |
Product Details anti-Paxillin AntibodyTarget Details Paxillin Application Details Handling References for anti-Paxillin antibody (ABIN2666198) Images |
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| Purification | The antibody was purified by antigen-affinity chromatography. |
| Clone | Poly6007 |
| Isotype | IgG |
| Plasmids, Primers & others | |
Target Details PaxillinProduct Details anti-Paxillin Antibody Application Details Handling References for anti-Paxillin antibody (ABIN2666198) Images back to top |
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| Antigen | |
| Alternative Name | Paxillin (PXN Antibody Abstract) |
| Background | Paxillin (also known as peroxisomal membrane protein 3) is a cytoplasmic protein with LIM metal-binding repeat homology and LIM domains. There are three isoforms of this protein designated as α, β, γ, approximate molecular weight 68 kD. Paxillin is localized to actin-membrane attachment at sites of cell adhesion to extracellular matrix (focal adhesion). This protein undergoes cell adhesion-dependent tyrosine phosphorylation. Paxillin has been shown to interact with FAK, vinculin, src, Crk, p210BRC / ABL, talin, and integrin-β1. The Poly6007 antibody recognizes human, mouse, and rat paxillin and has shown to be useful for Western blotting. |
| Pathways | MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling |
Application DetailsProduct Details anti-Paxillin Antibody Target Details Paxillin Handling References for anti-Paxillin antibody (ABIN2666198) Images back to top |
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| Application Notes | Optimal working dilution should be determined by the investigator. |
| Restrictions | For Research Use only |
HandlingProduct Details anti-Paxillin Antibody Target Details Paxillin Application Details References for anti-Paxillin antibody (ABIN2666198) Images back to top |
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| Format | Liquid |
| Buffer | phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Upon receipt, store frozen at -20°C. |
References for anti-Paxillin antibody (ABIN2666198)Product Details anti-Paxillin Antibody Target Details Paxillin Application Details Handling Images back to top |
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| Background publications |
Yao, Dashner, van Golen, van Golen: "RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility." in: Oncogene, Vol. 25, Issue 16, pp. 2285-96, 2006 Kirchner, Kam, Tzur, Bershadsky, Geiger: "Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption." in: Journal of cell science, Vol. 116, Issue Pt 6, pp. 975-86, 2003 Mazaki, Hashimoto, Sabe: "Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins." in: The Journal of biological chemistry, Vol. 272, Issue 11, pp. 7437-44, 1997 Leventhal, Shelden, Kim, Feldman: "Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance." in: The Journal of biological chemistry, Vol. 272, Issue 8, pp. 5214-8, 1997 |
ImagesProduct Details anti-Paxillin Antibody Target Details Paxillin Application Details Handling References for anti-Paxillin antibody (ABIN2666198) back to top |
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| Supplier Images |
anti-Paxillin (PXN) antibody
anti-Paxillin (PXN) antibody (Image 2)
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