anti-Mouse (Murine) Paxillin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Paxillin Antibody

Antigen
Paxillin (PXN) Antibodies
  • AW108311
  • AW123232
  • Pax
  • CG18061
  • CG18576
  • CG31794
  • CT40481
  • CT42454
  • DPaxillin
  • DPxn
  • DPxn37
  • Dmel\\CG31794
  • Dpax
  • DpaxA
  • PDLP
  • dPax
  • pax
  • wu:fw71f12
  • PXN
  • LOC100220858
  • paxillin
  • Paxillin
  • paxillin S homeolog
  • paxillin a
  • PXN
  • Pxn
  • Pax
  • pxn.S
  • pxna
  • LOC696336
  • pxn
Epitope
AA 456-472
67
65
38
30
24
17
15
14
11
10
7
6
6
6
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
458
247
230
27
12
10
8
5
5
5
4
3
1
1
1
1
Host
Rabbit
428
40
2
Clonality
Polyclonal
Conjugate
This Paxillin antibody is un-conjugated
15
13
13
13
13
13
13
6
6
4
4
4
4
4
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
340
129
116
53
46
46
27
18
11
8
3
2
1
Options

Available images

Catalog No. ABIN3032168
$ 452.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
17.5 ABIN3044187 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 456-472, C-Term Polyclonal 3
11.599518 ABIN498711 IHC (p) WB Rabbit pTyr31 Polyclonal 0
11.599518 ABIN498588 IF IHC (p) WB Rabbit Polyclonal 0
10 ABIN574184 IHC IHC (p) WB Rabbit IgG Tyr118 Polyclonal 0
10 ABIN745043 IF (p) IHC (p) WB Rabbit IgG AA 93-143, pTyr118 Polyclonal 0
9.445929 ABIN5947560 ICC IF IHC IHC (p) IP WB Rabbit IgG AA 1-100 SY23-02 0
7 ABIN6652575 IHC (p) WB Rabbit Tyr118 Polyclonal 3
7 ABIN6652115 IHC (p) WB Rabbit pTyr118 Polyclonal 4
7 ABIN2889052 ELISA IHC IHC (p) WB Rabbit IgG AA 15-64 Polyclonal 0
7 ABIN271779 EIA IHC (p) WB Rabbit Polyclonal 0
7 ABIN1738635 IHC (p) WB Rabbit IgG Tyr118 Polyclonal 0
4 ABIN5957430 ELISA IF IHC (p) WB Rabbit IgG Tyr31 Polyclonal 0
4 ABIN5957435 ELISA IHC (p) WB Rabbit IgG pTyr31 Polyclonal 0
1 ABIN745052 IHC (p) WB HRP Rabbit IgG AA 93-143, pTyr118 Polyclonal 0
1 ABIN745045 IHC (p) WB Biotin Rabbit IgG AA 93-143, pTyr118 Polyclonal 0
1 ABIN711230 IHC (p) WB HRP Rabbit IgG pSer178 Polyclonal 0
1 ABIN703520 IHC (p) WB HRP Rabbit IgG pTyr31 Polyclonal 0
1 ABIN2627435 ICC IHC IHC (fro) IHC (p) WB Rabbit IgG AA 456-472 Polyclonal 0
1 ABIN2892955 IF IHC IHC (p) WB Rabbit Leu25 Polyclonal 0
1 ABIN2893300 IHC IHC (p) WB Rabbit pTyr31 Polyclonal 0

General

Antigen Paxillin (PXN) Antibodies
Epitope AA 456-472
(67), (65), (38), (30), (24), (17), (15), (14), (11), (10), (7), (6), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(458), (247), (230), (27), (12), (10), (8), (5), (5), (5), (4), (3), (1), (1), (1), (1)
Host Rabbit
(428), (40), (2)
Clonality
Polyclonal
Conjugate This Paxillin antibody is un-conjugated
(15), (13), (13), (13), (13), (13), (13), (6), (6), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(340), (129), (116), (53), (46), (46), (27), (18), (11), (8), (3), (2), (1)
Supplier

Product Details anti-Paxillin Antibody

Target Details Paxillin Application Details Handling Images
Purification Antigen affinity
Immunogen Amino acids 456-472 (HEKDGKAYCRKDYFDMF) were used as the immunogen for this Paxillin antibody (100% homologous in human, mouse and rat).
Isotype IgG
Plasmids, Primers & others

Target Details Paxillin

Product Details anti-Paxillin Antibody Application Details Handling Images back to top
Antigen
Alternative Name Paxillin (PXN Antibody Abstract)
Background Paxillin is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge. Salgia et al.(1995) mapped the gene to 12q24 using fluorescence in situ hybridization.The C-terminal region of Paxillin contains four LIM domains that target paxillin to focal adhesions, it is presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region is rich in protein-protein interaction sites. The proteins that bind to Paxillin are diverse and include protein tyrosine kinases, such as Src and FAK, structural proteins, such as vinculin and actopaxin, and regulators of actin organization, such as COOL/PIX and PKL/GIT. Paxillin is tyrosine-phosphorylated by FAK and Src upon integrin engagement or growth factor stimulation, creating binding sites for the adapter protein Crk. The protein contains 4 LIM domains, a proline-rich domain containing a consensus SH3-binding site, and 3 potential SH2-binding sites.
UniProt P49023
Pathways MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling

Application Details

Product Details anti-Paxillin Antibody Target Details Paxillin Handling Images back to top
Application Notes The stated application concentrations are suggested starting amounts. Titration of the Paxillin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-Paxillin Antibody Target Details Paxillin Application Details Images back to top
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage -20 °C
Storage Comment After reconstitution, the Paxillin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Images

Product Details anti-Paxillin Antibody Target Details Paxillin Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) IHC-F testing of Paxillin antibody and rat kidney tissue
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) IHC-P: Paxillin antibody testing of human lung cancer tissue
Western Blotting (WB) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) Western blot testing of Paxillin antibody and Lane 1: 293T; 2: HeLa; 3: MCF-7; 4:...
Western Blotting (WB) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) Western blot testing of Paxillin antibody and Lane 1: 293T
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) IHC-F testing of Paxillin antibody and rat kidney tissue
Immunocytochemistry (ICC) image for anti-Paxillin (PXN) (AA 456-472) antibody (ABIN3032168) ICC testing of HeLa cells