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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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3.2908103 | ABIN2786821 | WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
3.2908103 | ABIN2707036 | IC IF IHC WB | Rabbit | Center | Log in to see | Polyclonal | 0 | |||
1 | ABIN3198314 | WB | Rabbit | pSer78 | Log in to see | Polyclonal | 0 | |||
1 | ABIN2744333 | ICC IF IHC (p) WB | Rabbit | Internal Region | Log in to see | Polyclonal | 0 | |||
1 | ABIN2972633 | WB | Rabbit | Center, pSer78 | Log in to see | Polyclonal | 0 | |||
1 | ABIN2972145 | IF/ICC IHC WB | Rabbit | Center | Log in to see | Polyclonal | 0 |
General |
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Antigen | serum/glucocorticoid Regulated Kinase 1 (SGK1) Antibodies |
Epitope | N-Term Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This SGK1 antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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1 reference available |
Supplier | Log in to see |
Product Details anti-SGK1 AntibodyTarget Details SGK1 Application Details Handling References for anti-SGK1 antibody (ABIN2786820) Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN983673 |
Sequence | ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE |
Predicted Reactivity | Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92% |
Characteristics | This is a rabbit polyclonal antibody against SGK1. It was validated on Western Blot using a cell lysate as a positive control. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human SGK1 |
Target Details SGK1Product Details anti-SGK1 Antibody Application Details Handling References for anti-SGK1 antibody (ABIN2786820) Images back to top |
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Antigen | |
Alternative Name | SGK1 (SGK1 Antibody Abstract) |
Background |
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell sur Alias Symbols: SGK Protein Interaction Partner: AKT1S1, YWHAQ, YWHAZ, MAPT, MTOR, CDKN1B, RPTOR, NEDD4L, Tmem109, Rabac1, GADD45G, UBC, MAGEA1, HSP90AA1, TMEM184C, WNK1, WNK2, WNK4, RAF1, PDPK1, NEDD4, TSC22D3, STUB1, HSPA4, ELAVL1, COMMD1, SYVN1, SCNN1B, RICTOR, PDK1, YPK1, IKBKG, CAMKK1, KCNJ1, GSK3A Protein Size: 431 |
Molecular Weight | 49 kDa |
Gene ID | 6446 |
NCBI Accession | NM_005627, NP_005618 |
UniProt | O00141 |
Pathways | MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway |
Application DetailsProduct Details anti-SGK1 Antibody Target Details SGK1 Handling References for anti-SGK1 antibody (ABIN2786820) Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 431 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-SGK1 Antibody Target Details SGK1 Application Details References for anti-SGK1 antibody (ABIN2786820) Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-SGK1 antibody (ABIN2786820)Product Details anti-SGK1 Antibody Target Details SGK1 Application Details Handling Images back to top |
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Background publications |
Pew, Zou, Brickley, Conzen: "Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway." in: Endocrinology, Vol. 149, Issue 5, pp. 2637-45, 2008 |
ImagesProduct Details anti-SGK1 Antibody Target Details SGK1 Application Details Handling References for anti-SGK1 antibody (ABIN2786820) back to top |
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Supplier Images |