Minichromosome Maintenance Complex Component 3 Products
(Minichromosome Maintenance Complex Component 3 (MCM3))
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
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Featured Minichromosome Maintenance Complex Component 3 Categories
Minichromosome Maintenance Complex Component 3 Antibodies
High quality antibodies with extensive validation data.
Minichromosome Maintenance Complex Component 3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Minichromosome Maintenance Complex Component 3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Minichromosome Maintenance Complex Component 3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (11)
Cat. No.
ABIN561761
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (7)
Cat. No.
ABIN3021327
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN7268540
Quantity
100 μL
Datasheet
Datasheet
Recommended Minichromosome Maintenance Complex Component 3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957841
Quantity
96 tests
Datasheet
Datasheet
Recommended Minichromosome Maintenance Complex Component 3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1310549
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3093723
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3133430
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Minichromosome Maintenance Complex Component 3 products
: "Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells." in: Toxicology letters, Vol. 209, Issue 1, pp. 58-66, (2012) (PubMed).: "High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma." in: Diagnostic pathology, Vol. 7, pp. 82, (2012) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." in: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).
: "BID binds to replication protein A and stimulates ATR function following replicative stress." in: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4298-309, (2011) (PubMed).
: "Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24." in: Blood, Vol. 111, Issue 10, pp. 5215-22, (2008) (PubMed).
Synonyms and alternative names related to Minichromosome Maintenance Complex Component 3
minichromosome maintenance complex component 3 (MCM3), MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) (mcm3), minichromosome maintenance complex component 3 (mcm3), minichromosome maintenance complex component 3 (Mcm3), Minichromosome maintenance 3 (Mcm3), minichromosome maintenance complex component 3 L homeolog (mcm3.L), MCM complex subunit Mcm3 (mcm3), AL033361, C80350, cb32, CG4206, chunp6867, dMCM3, Dmel\\CG4206, DmeMCM3, DmMCM3, DmMcm3, HCC5, MCM3, McM3, Mcmd, Mcp-PCR2, P1, P1-MCM3, P1.h, p1.m, PCR2, RLFB, wu:fa26g03, xmcm3Protein level used designations for Minichromosome Maintenance Complex Component 3
- DNA polymerase alpha holoenzyme-associated protein P1
- DNA replication factor MCM3
- DNA replication licensing factor MCM3
- MCM3 minichromosome maintenance deficient 3
- RLF subunit beta
- cervical cancer proto-oncogene 5
- hRlf beta subunit
- minichromosome maintenance deficient 3
- p102
- replication licensing factor, beta subunit
- zMCM3
- zygotic DNA replication licensing factor mcm3
- zygotic minichromosome maintenance protein 3
- P1-MCM3
- mini chromosome maintenance deficient
- CG4206-PA
- Mcm3-PA
- minichromosome maintenance 3
- minichromosome maintenance-PCR2
- P1 homolog
- XRLF subunit beta
- mMCM3
- maternal DNA replication licensing factor mcm3
- maternal minichromosome maintenance protein 3
- p100
- Minichromosome maintenance protein 3
Did you look for something else?
- MINA
- Milk Fat Globule-EGF Factor 8 Protein
- MIIP
- MIGF
- MIF4G Domain Containing
- MIF (Imalumab Biosimilar)
- MIF
- MIER3
- MIER2
- MIER1
- MIDN
- Midline 2
- Midkine (Neurite Growth-Promoting Factor 2)
- Mid1-Interacting Protein 1
- MID1
- MICU1
- Microtubule-Associated Protein, RP/EB Family, Member 3
- Microtubule Star
- Microtransferrinuria
- Microseminoprotein, Prostate Associated
- Minichromosome Maintenance Complex Component 5
- Minichromosome Maintenance Deficient 4
- Minute (2) 31A
- MIOS
- MIOX
- MIPEP
- MIPOL1
- MIR17HG
- MIR22HG
- MIR7-3HG
- MIS12
- MIS18 Binding Protein 1
- Mismatch Repair Protein 2
- MITD1
- MITF
- Mitochondrial ATPase Subunit 8
- Mitochondrial E3 Ubiquitin Protein Ligase 1
- Mitochondrial Import Receptor Subunit TOM20 homolog
- Mitochondrial Translation Elongation Factor EF-Ts Tsf1
- Mitochondrially Encoded ATP Synthase 8
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