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Minichromosome Maintenance Complex Component 5 Products

(Minichromosome Maintenance Complex Component 5 (MCM5))
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008].

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Featured Minichromosome Maintenance Complex Component 5 Categories

Minichromosome Maintenance Complex Component 5 Antibodies

High quality antibodies with extensive validation data.

Minichromosome Maintenance Complex Component 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Minichromosome Maintenance Complex Component 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Minichromosome Maintenance Complex Component 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ELISA, ICC
Validations
  • (6)
Cat. No. ABIN6263163
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (8)
Cat. No. ABIN7257096
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN6143644
Quantity 100 μL
Datasheet Datasheet

Recommended Minichromosome Maintenance Complex Component 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957842
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381303
Quantity 96 tests
Datasheet Datasheet

Recommended Minichromosome Maintenance Complex Component 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1310557
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093762
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134266
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Minichromosome Maintenance Complex Component 5 products

Panneerselvam, Pickering, Han, Li, Zheng, Zhang, Zhang, Fei: "Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate." in: Oncotarget, Vol. 5, Issue 5, pp. 1326-37, (2014) (PubMed).

Hubbi, Gilkes, Hu, Kshitiz, Ahmed, Semenza: "Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 32, pp. E3325-34, (2014) (PubMed).

Hubbi, Kshitiz, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Hubbi, Luo, Baek, Semenza: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).

Yan, Michael: "TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks." in: The Journal of cell biology, Vol. 184, Issue 6, pp. 793-804, (2009) (PubMed).

Adams, Medhurst, Dart, Lakin: "Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex." in: Oncogene, Vol. 25, Issue 28, pp. 3894-904, (2006) (PubMed).

Yan, Lindsay, Michael: "Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling." in: The Journal of cell biology, Vol. 173, Issue 2, pp. 181-6, (2006) (PubMed).

Dart, Adams, Akerman, Lakin: "Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16433-40, (2004) (PubMed).

Forsburg: "Eukaryotic MCM proteins: beyond replication initiation." in: Microbiology and molecular biology reviews : MMBR, Vol. 68, Issue 1, pp. 109-31, (2004) (PubMed).

Synonyms and alternative names related to Minichromosome Maintenance Complex Component 5

DNA replication licensing factor MCM5 (BBOV_IV010040), minichromosome maintenance complex component 5 S homeolog (mcm5.S), minichromosome maintenance complex component 5 (MCM5), DNA replication licensing factor Mcm5 (AFUA_5G02520), DNA replication licensing factor mcm5 (NCU01171), DNA replication licensing factor MCM5 (PVX_084615), DNA replication licensing factor Mcm5 (LOC5576119), DNA replication licensing factor mcm5 (CpipJ_CPIJ008678), DNA replication licensing factor MCM5 (Bm1_24480), DNA replication licensing factor MCM5 (CMU_022890), minichromosome maintenance complex component 5 (Mcm5), minichromosome maintenance complex component 5 (mcm5), DNA replication licensing factor MCM5 (TP01_0722), MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) (mcm5), minichromosome maintenance complex component 5 L homeolog (mcm5.L), Minichromosome maintenance 5 (Mcm5), DNA replication licensing factor mcm-5 (mcm-5), 23.m06024, AA617332, Afu5g02520, AI324988, AL033333, cdc46, CDC46, Cdc46, CG4082, DmCDC46, DmCDC465, Dmel\\CG4082, DmeMCM5, DmMCM5, DmMcm5, mCD46, mCDC46, mcm5, MCM5, McM5, Mcmd5, NCU01171.1, P1-CDC46, PCR4, wu:fb34a06, xmcm5

Protein level used designations for Minichromosome Maintenance Complex Component 5

  • DNA replication licensing factor mcm5-B
  • xMCM5-B
  • xCDC46-B
  • CDC46 homolog B
  • CDC46 homolog
  • DNA replication licensing factor MCM5
  • MCM5 minichromosome maintenance deficient 5, cell division cycle 46
  • minichromosome maintenance deficient 5 (cell division cycle 46)
  • DNA replication licensing factor mcm5
  • mini chromosome maintenance deficient 5
  • minichromosome maintenance deficient 5, cell division cycle 46
  • minichromosome maintenance deficient protein 5
  • CDC46 homolog A
  • CDC46p
  • DNA replication licensing factor mcm5-A
  • p92
  • xCDC46-A
  • xMCM5-A
  • CG4082-PA
  • Mcm5-PA
  • mini-chromosome maintenance 5
  • minichromosome maintenance 5
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