MDS1 and EVI1 Complex Locus Products
(MDS1 and EVI1 Complex Locus (MECOM))
Categories
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Featured MDS1 and EVI1 Complex Locus Categories
MDS1 and EVI1 Complex Locus Antibodies
High quality antibodies with extensive validation data.
MDS1 and EVI1 Complex Locus ELISA Kits
Reliable ELISA kits for a wide range of species.
MDS1 and EVI1 Complex Locus Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MDS1 and EVI1 Complex Locus Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7074575
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN5583378
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN2777403
Quantity
100 μL
Datasheet
Datasheet
Recommended MDS1 and EVI1 Complex Locus ELISA Kits
Recommended MDS1 and EVI1 Complex Locus Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310620
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310610
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310612
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MDS1 and EVI1 Complex Locus products
: "Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia." in: Cancer cell, Vol. 30, Issue 1, pp. 59-74, (2016) (PubMed).: "The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006259, (2016) (PubMed).
: "Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia." in: Haematologica, Vol. 97, Issue 4, pp. 543-50, (2012) (PubMed).
: "Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes." in: Journal of leukocyte biology, Vol. 86, Issue 4, pp. 813-22, (2009) (PubMed).
Synonyms and alternative names related to MDS1 and EVI1 Complex Locus
MDS1 and EVI1 complex locus (MECOM), MDS1 and EVI1 complex locus (Mecom), MDS1 and EVI1 complex locus (mecom), MDS1 and EVI1 complex locus L homeolog (mecom.L), MDS1 and EVI1 complex locus S homeolog (mecom.S), AML1-EVI-1, D630039M04Rik, Evi-1, evi-1, EVI1, Evi1, evi1, evi1-B, im:7140716, Jbo, Mds, MDS1, Mds1, MDS1-EVI1, Mds1-Evi1, mecom, mecom-a, mecom-b, PRDM3, Prdm3, prdm3, xEvi-1, Znfpr1b1Protein level used designations for MDS1 and EVI1 Complex Locus
- AML1-EVI-1 fusion protein
- MDS1 and EVI1 complex locus protein EVI1
- MDS1 and EVI1 complex locus protein MDS1
- ecotropic virus integration site 1 protein homolog
- myelodysplasia syndrome-associated protein 1
- oncogene EVI1
- zinc finger protein Evi1
- ecotropic viral integration site 1
- ecotropic virus integration site 1 protein
- myelodysplasia syndrome 1 homolog
- myelodysplasia syndrome 1 protein homolog
- PR domain containing 3
- MDS1 and EVI1 complex locus
- MDS1 and EVI1 complex locus protein EVI1-like
- MDS1 and EVI1 complex locus protein EVI1-A
- ecotropic virus integration site 1 protein homolog-A
- myelodysplasia syndrome 1-ectopic viral integration site 1
- Ecotropic virus integration site 1 protein homolog-B
- MDS1 and EVI1 complex locus protein EVI1-B
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