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This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
translation initiation factor eIF-2B subunit alpha
, Translation initiation factor eIF-2B subunit alpha
, translation initiation factor eif-2b subunit alpha
, eIF-2B GDP-GTP exchange factor subunit alpha
, eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa)
, GTP-exchange protein