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|Antigen||Cytoplasmic Linker Associated Protein 1 (CLASP1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CLASP1 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-CLASP1 AntibodyTarget Details CLASP1 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human CLASP1|
Target Details CLASP1Product Details anti-CLASP1 Antibody Application Details Handling Images back to top
|Alternative Name||Clasp1 (CLASP1 Antibody Abstract)|
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Synonyms: CLAP1_HUMAN, clasp1, CLIP associating protein 1, CLIP associating protein CLASP1, CLIP-associating protein 1, Cytoplasmic linker associated protein 1, Cytoplasmic linker-associated protein 1, hOrbit1, MAST1, Multiple asters 1, Multiple asters homolog 1, Protein Orbit homolog 1.
|Pathways||Microtubule Dynamics, M Phase, Maintenance of Protein Location|
Application DetailsProduct Details anti-CLASP1 Antibody Target Details CLASP1 Handling Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-CLASP1 Antibody Target Details CLASP1 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|